Bioorganic & medicinal chemistry

Label

• Bioorganic & medicinal chemistry (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Synthesis and activity of fibrillogenesis peptide inhibitors related tothe 17-21 b-amyloid sequence (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fmoc-protected iminosugar modified asparagine derivatives as building blocks for glycomimetics-containing peptides (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Design, synthesis, binding and molecular modeling studies of new potent ligands of cannabinoid receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Targeting integrins: insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids (Articolo in rivista) (Prodotto della ricerca)
• High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones. (Articolo in rivista) (Prodotto della ricerca)
• Non-peptide NK(1) receptor ligands based on the 4-phenylpyridine moiety. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Designed calix[8]arene-based ligand for selective tryptase surface recognition (Articolo in rivista) (Prodotto della ricerca)
• The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamide analogs with phenyl rings in the polar head group region (Articolo in rivista) (Prodotto della ricerca)
• Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes. (Articolo in rivista) (Prodotto della ricerca)
• Selective interactions of perylene derivatives having different side chainswith inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens (Articolo in rivista) (Prodotto della ricerca)
• 3-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-6-substituted-3,6-diazabicyclo[3.1.1]hep (Articolo in rivista) (Prodotto della ricerca)
• Synthesis of Bicyclic Molecular Scaffolds (BTAa). An Investigation Towards New Selective MMP-12 Inhibitors (Articolo in rivista) (Prodotto della ricerca)
• Synthesis of novel diazatricyclodecanes (DTDs). Effects of structural variation at the C3' allyl end and at the phenyl ring of the cinnamyl chain on mu-receptor affinity and opioid antinociception (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Sulfonamide inhibition studies of two beta-carbonic anhydrases from the bacterial pathogen Legionella pneumophila (Articolo in rivista) (Prodotto della ricerca)
• Cloning, characterization and anion inhibition study of the delta-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii (Articolo in rivista) (Prodotto della ricerca)
• Design, synthesis and in vitro evaluation of new naphthylnitrobutadienes with potential antiproliferative activity: towards a structure/activity correlation. (Articolo in rivista) (Prodotto della ricerca)
• Sulfonates-PMMA nanoparticles conjugates: A versatile system for multimodal application (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis, labeling, and biological evaluation of halogenated 2 quinolinecarboxamides as potential radioligands for the visualization of peripheral benzodiazepine receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• alpha-Peptide/beta-sulfonamidopeptide hybrids: Analogs of the chemotactic agent for-Met-Leu-Phe-OMe (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Antimicrobial and Anti-Lipase Activity of Quercetin and Its C2-C16 3-O-Acyl-Esters (Articolo in rivista) (Prodotto della ricerca)
• 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family. (Articolo in rivista) (Prodotto della ricerca)
• TRPV1 modulators: Structure-activity relationships using a rational combinatorial approach (Articolo in rivista) (Prodotto della ricerca)
• Astersedifolioside A-C, three new oleane-type saponins with antiproliferative activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: Design, synthesis, structure–affinity and structure–selectivity relationships (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Binding ability of a thymine-functionalized oligolysine towards nucleic acids (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Research on L-nucleosides. Synthesis and biological evaluation of a series of L- and D-2',3'-dideoxy-3'-[tris(methylthio)methyl]-beta-pentofuranosyl nucleosides. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Exploring the interest of 1, 2-dithiolane ring system in peptide chemistry. Synthesis of a chemotactic tripeptide and x-ray crystal structure of a 4-amino-1, 2-dithiolane-4-carboxylic acid derivative (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-affinity relationship studies on arylpiperazine derivatives related to quizapine as serotonin transporter ligands. Molecular basis of the selectivity SERT/5HT3 receptor (Articolo in rivista) (Prodotto della ricerca)
• Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis, biophysical characterization and anti-HIV activity of d(TG(3)AG) Quadruplexes bearing hydrophobic tails at the 5 '-end (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors (Articolo in rivista) (Prodotto della ricerca)
• A new and efficient synthesis of substituted 6-(2-dialkylamono)ethyl pyrimidine and 4-N, N-dialkyl-6-vinyl-cytosine derivatives and evaluation of their anti-rubella activity. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Insights into MAPK p38a DFG flip mechanism by accelerated molecular dynamics (Articolo in rivista) (Prodotto della ricerca)
• Improved synthesis of daunomycin conjugates with triplex-forming oligonucleotides. The polypurine tract of HIV-1 as a target. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Evaluating geometrical trans lipid isomer for an antisense strategy: synthesis of all-trans anandamide and activity on platelet aggregation (Articolo in rivista) (Prodotto della ricerca)
• Novel bioactive metabolites of dipyrone (metamizol). (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Proline-Glutamate Chimeras in Isopeptides., Synthesis and Biological Evaluation of Conformationally Restricted Glutathione Analogues (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Physicochemical and biological study of selected hydrophobic polyethylenimine-based polycationic liposomes and their complexes with DNA. (Articolo in rivista) (Prodotto della ricerca)
• Synthesis of DEHP metabolites as biomarkers for GC–MS evaluation of phthalates as endocrine disrupters (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Efficient and highly stereoselective synthesis of a betalactam inhibitor of the serine protease prostate-specific antigen (Articolo in rivista) (Prodotto della ricerca)
• Quinazoline-sulfonamides with potent inhibitory activity against the alpha-carbonic anhydrase from Vibrio cholerae (Articolo in rivista) (Prodotto della ricerca)
• Dual Src and Abl inhibitors target wild type Abl and the AblT315I Imatinib-resistant mutant with different mechanisms. (Articolo in rivista) (Prodotto della ricerca)
• The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region (Articolo in rivista) (Prodotto della ricerca)
• An o-nitrobenzyl scaffold for peptide ligation: synthesis and applications (Articolo in rivista) (Prodotto della ricerca)
• Anion inhibition study of the beta-carbonic anhydrase (CahB1) from the cyanobacterium Coleofasciculus chthonoplastes (ex-Microcoleus chthonoplastes) (Articolo in rivista) (Prodotto della ricerca)
• Phthalazine PDE IV inhibitors: Conformational study of some 6-methoxy-1,4-disubstituted derivatives (Articolo in rivista) (Prodotto della ricerca)
• Malondialdehyde scavenging and aldose-derived Schiff bases transglycation properties of synthetic histidyl-hydrazide carnosine analogs (Articolo in rivista) (Prodotto della ricerca)
• New antiviral drugs for the treatment of the common cold (Articolo in rivista) (Prodotto della ricerca)
• Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Specific interactions with intra- and intermolecular G-quadruplex DNA structures by hydrosoluble coronene derivatives: A new class of telomerase inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibitory effect of beta-diketones and their metal complexes on TNF-alpha induced expression of ICAM-1 on human endothelial cells (Articolo in rivista) (Prodotto della ricerca)
• Synthesis and biological evaluation of cyclic and branched peptide analogues as ligands for cholecystokinin type 1 receptor (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Design, modelling, synthesis and biological evaluation of peptidomimetic phosphinates as inhibitors of matrix metalloproteinases MMP-2 and MMP-8. (Articolo in rivista) (Prodotto della ricerca)
• Stereocontrolled synthesis and biological activity of two diastereoisomers of the potent HIV-1 protease inhibitor saquinavir (Articolo in rivista) (Prodotto della ricerca)
• Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Induction and Memory of Chirality in Porphyrin Hetero-Aggregates: the Role of the Central Metal Ion. (Articolo in rivista) (Prodotto della ricerca)
• Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. (Articolo in rivista) (Prodotto della ricerca)
• Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase. (Articolo in rivista) (Prodotto della ricerca)
• The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase (Articolo in rivista) (Prodotto della ricerca)
• Novel sterically hindered cannabinoid CB1 receptor ligands. (Articolo in rivista) (Prodotto della ricerca)
• Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the beta-class (PgiCAb) versus the gamma-class (PgiCA) enzymes. (Articolo in rivista) (Prodotto della ricerca)
• Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5?-Reductase 1 (Articolo in rivista) (Prodotto della ricerca)
• Biocatalysed synthesis of b-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties (Articolo in rivista) (Prodotto della ricerca)
• 5-(Trifluoromethyl)-beta-l-2'-deoxyuridine, the L-enantiomer of trifluorothymidine: stereospecific synthesis and antiherpetic evaluations. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Reassessing the melatonin pharmacophore--enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue (Articolo in rivista) (Prodotto della ricerca)
• Synthesis and biological evaluation of 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives as new ligands of cannabinoid receptors. (Articolo in rivista) (Prodotto della ricerca)
• Trans fatty acids and radical stress: what are the real culprits? (Articolo in rivista) (Prodotto della ricerca)
• Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A SPR strategy for high-throughput ligand screenings based on synthetic peptides mimicking a selected subdomain of the target protein: A proof of concept on HER2 receptor (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of the amino sugar in the DNA binding of disaccharide anthracyclines: crystal structure of the complex MAR70/d(CGATCG). (Articolo in rivista) (Prodotto della ricerca)
• Synthesis and activity studies of analogues of the rat selective toxicant norbormide (Articolo in rivista) (Prodotto della ricerca)
• Stereocontrolled Synthesis and Biological Activity of two Diastereoisomers of the Potent HIV-1 Protease Inhibitor Saquinavir (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Homo- and heterodimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part I: Synthesis (Articolo in rivista) (Prodotto della ricerca)
• Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Antimalarial and antiproliferative evaluation of bis-steroidal tetraoxanes (Articolo in rivista) (Prodotto della ricerca)

Alternative label

• Bioorganic and medicinal chemistry (literal)
• Bioorg. med. chem. (literal)
• Bioorganic & medicinal chemistry. (literal)
• Biomed. chem (literal)

Language

• eng (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#issn

• 0968-0896 (literal)

Preferred label

• Bioorganic & medicinal chemistry (literal)

Publisher

• Pergamon, Oxford : GBR (literal)

Incoming links:

Rivista

• Synthesis and biological evaluation of cyclic and branched peptide analogues as ligands for cholecystokinin type 1 receptor (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Proline-Glutamate Chimeras in Isopeptides., Synthesis and Biological Evaluation of Conformationally Restricted Glutathione Analogues (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase (Articolo in rivista) (Prodotto della ricerca)
• Synthesis of DEHP metabolites as biomarkers for GC–MS evaluation of phthalates as endocrine disrupters (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Reassessing the melatonin pharmacophore--enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue (Articolo in rivista) (Prodotto della ricerca)
• Design, modelling, synthesis and biological evaluation of peptidomimetic phosphinates as inhibitors of matrix metalloproteinases MMP-2 and MMP-8. (Articolo in rivista) (Prodotto della ricerca)
• Research on L-nucleosides. Synthesis and biological evaluation of a series of L- and D-2',3'-dideoxy-3'-[tris(methylthio)methyl]-beta-pentofuranosyl nucleosides. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 5-(Trifluoromethyl)-beta-l-2'-deoxyuridine, the L-enantiomer of trifluorothymidine: stereospecific synthesis and antiherpetic evaluations. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. (Articolo in rivista) (Prodotto della ricerca)
• Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase. (Articolo in rivista) (Prodotto della ricerca)
• Structure-affinity relationship studies on arylpiperazine derivatives related to quizapine as serotonin transporter ligands. Molecular basis of the selectivity SERT/5HT3 receptor (Articolo in rivista) (Prodotto della ricerca)
• 11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Non-peptide NK(1) receptor ligands based on the 4-phenylpyridine moiety. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis and activity of fibrillogenesis peptide inhibitors related tothe 17-21 b-amyloid sequence (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis of Bicyclic Molecular Scaffolds (BTAa). An Investigation Towards New Selective MMP-12 Inhibitors (Articolo in rivista) (Prodotto della ricerca)
• Phthalazine PDE IV inhibitors: Conformational study of some 6-methoxy-1,4-disubstituted derivatives (Articolo in rivista) (Prodotto della ricerca)
• New antiviral drugs for the treatment of the common cold (Articolo in rivista) (Prodotto della ricerca)
• 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family. (Articolo in rivista) (Prodotto della ricerca)
• Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dual Src and Abl inhibitors target wild type Abl and the AblT315I Imatinib-resistant mutant with different mechanisms. (Articolo in rivista) (Prodotto della ricerca)
• Astersedifolioside A-C, three new oleane-type saponins with antiproliferative activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis and biological evaluation of 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives as new ligands of cannabinoid receptors. (Articolo in rivista) (Prodotto della ricerca)
• Synthesis of novel diazatricyclodecanes (DTDs). Effects of structural variation at the C3' allyl end and at the phenyl ring of the cinnamyl chain on mu-receptor affinity and opioid antinociception (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Physicochemical and biological study of selected hydrophobic polyethylenimine-based polycationic liposomes and their complexes with DNA. (Articolo in rivista) (Prodotto della ricerca)
• Synthesis, labeling, and biological evaluation of halogenated 2 quinolinecarboxamides as potential radioligands for the visualization of peripheral benzodiazepine receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Selective interactions of perylene derivatives having different side chainswith inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors (Articolo in rivista) (Prodotto della ricerca)
• Antimicrobial and Anti-Lipase Activity of Quercetin and Its C2-C16 3-O-Acyl-Esters (Articolo in rivista) (Prodotto della ricerca)
• The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamide analogs with phenyl rings in the polar head group region (Articolo in rivista) (Prodotto della ricerca)
• Designed calix[8]arene-based ligand for selective tryptase surface recognition (Articolo in rivista) (Prodotto della ricerca)
• Malondialdehyde scavenging and aldose-derived Schiff bases transglycation properties of synthetic histidyl-hydrazide carnosine analogs (Articolo in rivista) (Prodotto della ricerca)
• Design, synthesis, binding and molecular modeling studies of new potent ligands of cannabinoid receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Stereocontrolled Synthesis and Biological Activity of two Diastereoisomers of the Potent HIV-1 Protease Inhibitor Saquinavir (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel sterically hindered cannabinoid CB1 receptor ligands. (Articolo in rivista) (Prodotto della ricerca)
• Stereocontrolled synthesis and biological activity of two diastereoisomers of the potent HIV-1 protease inhibitor saquinavir (Articolo in rivista) (Prodotto della ricerca)
• Inhibitory effect of beta-diketones and their metal complexes on TNF-alpha induced expression of ICAM-1 on human endothelial cells (Articolo in rivista) (Prodotto della ricerca)
• Fmoc-protected iminosugar modified asparagine derivatives as building blocks for glycomimetics-containing peptides (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• An o-nitrobenzyl scaffold for peptide ligation: synthesis and applications (Articolo in rivista) (Prodotto della ricerca)
• 1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: Design, synthesis, structure–affinity and structure–selectivity relationships (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A new and efficient synthesis of substituted 6-(2-dialkylamono)ethyl pyrimidine and 4-N, N-dialkyl-6-vinyl-cytosine derivatives and evaluation of their anti-rubella activity. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Design, synthesis and in vitro evaluation of new naphthylnitrobutadienes with potential antiproliferative activity: towards a structure/activity correlation. (Articolo in rivista) (Prodotto della ricerca)
• Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones. (Articolo in rivista) (Prodotto della ricerca)
• Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 3-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-6-substituted-3,6-diazabicyclo[3.1.1]hep (Articolo in rivista) (Prodotto della ricerca)
• Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes. (Articolo in rivista) (Prodotto della ricerca)
• Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Improved synthesis of daunomycin conjugates with triplex-forming oligonucleotides. The polypurine tract of HIV-1 as a target. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Evaluating geometrical trans lipid isomer for an antisense strategy: synthesis of all-trans anandamide and activity on platelet aggregation (Articolo in rivista) (Prodotto della ricerca)
• Insights into MAPK p38a DFG flip mechanism by accelerated molecular dynamics (Articolo in rivista) (Prodotto della ricerca)
• Antimalarial and antiproliferative evaluation of bis-steroidal tetraoxanes (Articolo in rivista) (Prodotto della ricerca)
• Efficient and highly stereoselective synthesis of a betalactam inhibitor of the serine protease prostate-specific antigen (Articolo in rivista) (Prodotto della ricerca)
• Targeting integrins: insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids (Articolo in rivista) (Prodotto della ricerca)
• Trans fatty acids and radical stress: what are the real culprits? (Articolo in rivista) (Prodotto della ricerca)
• Synthesis and activity studies of analogues of the rat selective toxicant norbormide (Articolo in rivista) (Prodotto della ricerca)
• Biocatalysed synthesis of b-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties (Articolo in rivista) (Prodotto della ricerca)
• Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens (Articolo in rivista) (Prodotto della ricerca)
• Sulfonates-PMMA nanoparticles conjugates: A versatile system for multimodal application (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Specific interactions with intra- and intermolecular G-quadruplex DNA structures by hydrosoluble coronene derivatives: A new class of telomerase inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• alpha-Peptide/beta-sulfonamidopeptide hybrids: Analogs of the chemotactic agent for-Met-Leu-Phe-OMe (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Induction and Memory of Chirality in Porphyrin Hetero-Aggregates: the Role of the Central Metal Ion. (Articolo in rivista) (Prodotto della ricerca)
• Novel bioactive metabolites of dipyrone (metamizol). (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A SPR strategy for high-throughput ligand screenings based on synthetic peptides mimicking a selected subdomain of the target protein: A proof of concept on HER2 receptor (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of the amino sugar in the DNA binding of disaccharide anthracyclines: crystal structure of the complex MAR70/d(CGATCG). (Articolo in rivista) (Prodotto della ricerca)
• Exploring the interest of 1, 2-dithiolane ring system in peptide chemistry. Synthesis of a chemotactic tripeptide and x-ray crystal structure of a 4-amino-1, 2-dithiolane-4-carboxylic acid derivative (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Homo- and heterodimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part I: Synthesis (Articolo in rivista) (Prodotto della ricerca)
• Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• TRPV1 modulators: Structure-activity relationships using a rational combinatorial approach (Articolo in rivista) (Prodotto della ricerca)
• Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5?-Reductase 1 (Articolo in rivista) (Prodotto della ricerca)
• Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the beta-class (PgiCAb) versus the gamma-class (PgiCA) enzymes. (Articolo in rivista) (Prodotto della ricerca)
• Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Sulfonamide inhibition studies of two beta-carbonic anhydrases from the bacterial pathogen Legionella pneumophila (Articolo in rivista) (Prodotto della ricerca)
• Cloning, characterization and anion inhibition study of the delta-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii (Articolo in rivista) (Prodotto della ricerca)
• Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region (Articolo in rivista) (Prodotto della ricerca)
• Synthesis, biophysical characterization and anti-HIV activity of d(TG(3)AG) Quadruplexes bearing hydrophobic tails at the 5 '-end (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Binding ability of a thymine-functionalized oligolysine towards nucleic acids (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anion inhibition study of the beta-carbonic anhydrase (CahB1) from the cyanobacterium Coleofasciculus chthonoplastes (ex-Microcoleus chthonoplastes) (Articolo in rivista) (Prodotto della ricerca)
• Quinazoline-sulfonamides with potent inhibitory activity against the alpha-carbonic anhydrase from Vibrio cholerae (Articolo in rivista) (Prodotto della ricerca)
• Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)