Organisation of the Hb1 genes of the Antarctic skate Bathyraja eatonii: new insights into the evolution of globin genes (Articolo in rivista)

Type
Label
  • Organisation of the Hb1 genes of the Antarctic skate Bathyraja eatonii: new insights into the evolution of globin genes (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.gene.2007.10.002 (literal)
Alternative label
  • Marino K.; Boschetto L.; de Pascale D.; Cocca E. (2007)
    Organisation of the Hb1 genes of the Antarctic skate Bathyraja eatonii: new insights into the evolution of globin genes
    in Gene (Amst.); ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, AMSTERDAM (Paesi Bassi)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Marino K.; Boschetto L.; de Pascale D.; Cocca E. (literal)
Pagina inizio
  • 199 (literal)
Pagina fine
  • 208 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://www.sciencedirect.com/science/article/pii/S0378111907005094 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 406 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 10 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 1-2 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Institute of Protein Biochemistry, C.N.R., Via P. Castellino 111, I-80131 Naples, Italy (literal)
Titolo
  • Organisation of the Hb1 genes of the Antarctic skate Bathyraja eatonii: new insights into the evolution of globin genes (literal)
Abstract
  • An extensive investigation of the organisation of globin genes has greatly contributed to the understanding of universal mechanisms of gene evolution and expression. Cartilaginous fish are the first organisms that have evolved the tetrameric form of hemoglobin (Hb). So far, there has been absolute lack of data about globin genes in chondrichthyans. Bathyraja is the dominant rajid south of 60‹S. In the framework of the investigations on globin genes of Antarctic red-blooded and Hb-less fish we obtained the cloning of the ƒ¿- and ƒÀ-globin cDNAs of the main Hb (Hb 1) of the skate Bathyraja eatonii. Then, a genomic fragment of 6.2 kb was isolated where the Hb 1 ƒ¿ and ƒÀ genes are linked in a tail-to-head (3Œ to 5Œ) orientation. The ƒÀ-globin gene promoter region and the chromosomal organisation of the Hb 1 genes of B. eatonii have been compared to their homologues in other vertebrates. The finding of a tail-to-head linkage of the Hb 1 ƒ¿- and ƒÀ-globin genes in B. eatonii is the first characterisation of the organisation of globin genes in chondrichthyes; such finding offers a novel contribution to the understanding of the evolution of this class of genes. Moreover, the characterisation of chondrichthyan genes is very important for gaining insight into the ancestral state of vertebrate genomes. (literal)
Editore
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Editore di
Insieme di parole chiave di
data.CNR.it