Time course of perfusion and wall motion changes after CRT in patients with heart failure (Contributo in atti di convegno)

Type
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  • Time course of perfusion and wall motion changes after CRT in patients with heart failure (Contributo in atti di convegno) (literal)
Anno
  • 2006-01-01T00:00:00+01:00 (literal)
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  • Gimelli A.; Frumento P.; Stanislao M.; Valle G.; Zanco P.; Startari U.; Piacenti M.; Marzullo P. (2006)
    Time course of perfusion and wall motion changes after CRT in patients with heart failure
    in World Congress of Cardiology, Barcellona
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Gimelli A.; Frumento P.; Stanislao M.; Valle G.; Zanco P.; Startari U.; Piacenti M.; Marzullo P. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: World Congress of Cardiology (Barcellona, 2-6 settembre 2006). Proceedings, pp. P1328-. European Society of Cardiology 1997-2005 (ed.). ESC Congress Reports, 2006. (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
  • ABSTRACT: Rationale: Cardiac resynchronization therapy (CRT) may induce significant changes in regional wall motion and perfusion in patients with heart failure. There are currently no data on the relationship between these variables and recovery of ventricular function at short and medium term follow-up. Methods: To this purpose, 36 patients with idiopathic (22) or ischemic (14) cardiomyopathy (mean age 70±8 yrs, 24 male), were studied by Gated SPECT before (T0), within 2 months (T1) and 6 months (T2) after CRT. Results: NYHA Class improved in all but 4 patients at T1 and did not change at T2. SPECT showed significant reperfusion at T1 in 92% of patients without significant changes at T2. Baseline end-diastolic volume index obtained by gated SPECT modulated at T1 the increase of EF, (p.001), the reduction of end systolic volume index (p.01), the improvement of regional wall motion (p.001) and ventricular wall thickening (p.002). Beyond T1, these variables showed only minor changes at T2. Finally, despite CRT induced significant reperfusion at T1 in the majority of patients, extension of perfusion defects at T0 correlated well with EF improvement after CRT (p.05 at T1; T1 vs T2 (literal)
Titolo
  • Time course of perfusion and wall motion changes after CRT in patients with heart failure (literal)
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