Sustained response with negative serum HCV-mRNA and disappearance of antibodies after interferon-alpha therapy in a kidney transplant recipient with chronic active viral hepatitis C (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Sustained response with negative serum HCV-mRNA and disappearance of antibodies after interferon-alpha therapy in a kidney transplant recipient with chronic active viral hepatitis C (Articolo in rivista) (literal)

Anno

• 2003-01-01T00:00:00+01:00 (literal)

Alternative label

• Luciani, G.; Bossola, M.; Muscaritoli, M.; Panocchia, N.; Ferrante, A.; Nanni, G.; Piccioni, E.; Tazza, L.; Grillo, R.L.; Rossi, F. F.; Castagneto, M. (2003)
  Sustained response with negative serum HCV-mRNA and disappearance of antibodies after interferon-alpha therapy in a kidney transplant recipient with chronic active viral hepatitis C
  in JN. Journal of Nephrology (Milano, 1992)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Luciani, G.; Bossola, M.; Muscaritoli, M.; Panocchia, N.; Ferrante, A.; Nanni, G.; Piccioni, E.; Tazza, L.; Grillo, R.L.; Rossi, F. F.; Castagneto, M. (literal)

Pagina inizio

• 417 (literal)

Pagina fine

• 420 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 16 (literal)

Rivista

• JN. Journal of Nephrology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• Sustained response with negative serum HCV-mRNA and disappearance of antibodies after interferon-alpha therapy in a kidney transplant recipient with chronic active viral hepatitis C (literal)

Abstract

• BACKGROUND: The use of interferon-alpha (IFN-alpha) to treat viral hepatitis C (HCV) occurring in kidney transplant recipients is controversial. This study reports an HCV patient successfully treated with IFN-alpha therapy achieving sustained response, negative serum HCV-mRNA and the disappearance of HCV antibodies, without impairment of renal function. METHOD: A young kidney transplant recipient developed a proven HCV infection 70 months post-transplantation. The patient received IFN-alpha therapy, and for a 32-month follow-up period was evaluated clinically, serologically and virologically. RESULTS: IFN-alpha therapy resulted in normal transaminase activities within 2 months. Serum HCV-mRNA was negative after 4 weeks of treatment and is still negative. Ten months after IFN-alpha therapy withdrawal, the enzyme immunoassay revealed that HCV antibodies (HCVAb) were absent in the serum. IFN-alpha therapy was safe, well tolerated and renal function was not impaired (literal)

Prodotto di

• Istituto di analisi dei sistemi ed informatica \"Antonio Ruberti\" (IASI) (Istituto)
• Modelli e Metodi Matematici in Fisiopatologia (ME.P06.002.001) (Modulo)

Autore CNR

• MARCO CASTAGNETO (Persona)

Incoming links:

Prodotto

• Istituto di analisi dei sistemi ed informatica \"Antonio Ruberti\" (IASI) (Istituto)
• Modelli e Metodi Matematici in Fisiopatologia (ME.P06.002.001) (Modulo)

Autore CNR di

• MARCO CASTAGNETO (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• JN. Journal of Nephrology (Rivista)