Serum thyroglobulin mesurement in the follow-up of patients treated for differentiated thyroid cancer (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Serum thyroglobulin mesurement in the follow-up of patients treated for differentiated thyroid cancer (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Alternative label

• Zucchelli G.; Iervasi A.; Ferdeghini M.; Iervasi G. (2009)
  Serum thyroglobulin mesurement in the follow-up of patients treated for differentiated thyroid cancer
  
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Zucchelli G.; Iervasi A.; Ferdeghini M.; Iervasi G. (literal)

Pagina inizio

• 482 (literal)

Pagina fine

• 489 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 53 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• In: The Quarterly Journal of Nuclear Medicine and Molecular Imaging, vol. 53 pp. 482 - 489. Minerva Medica, 2009. (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• CNR-IFC, Pisa, Nuclear Medicine University of Verona, Verona (Italy) (literal)

Titolo

• Serum thyroglobulin mesurement in the follow-up of patients treated for differentiated thyroid cancer (literal)

Abstract

• Determination of thyroglobulin (Tg)in serum represents a key element in the follow-up of patients treated for differentiated thyroid cancer (DTC). The sensitivity and the specificity of the assay strongly affects the clinical impact.Most of patients are disease-free after thyroidectomy and iodine ablation; 15% of them show over time persistent or recurrent disease; of these, 5% due to worsening of disease. This implies that the follow-up procedures should have a high negative predicitve value to reduce as possible the unnecessary diagnostic tools and a high positive predictive value to identify the few patients with persistent/recurrent disease. The recent international guidelines are based on thyroglobulin measurement after thyroid-stimulating hormone (TSH) stimulation. More recent studies suggest that follow up based on serial measurements of basal (i.e. unstimulated)Tg show a higher predictive value than the single measurement after stimulation. Large and multicenter studies are necessary to modify the current guidelines (literal)

Prodotto di

• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR

• GIANCARLO ZUCCHELLI (Unità di personale interno)
• ANNALISA IERVASI (Unità di personale interno)
• GIORGIO IERVASI (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "Serum thyroglobulin mesurement in the follow-up of patients treated for differentiated thyroid cancer" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto di fisiologia clinica (IFC) (Istituto)

Autore CNR di

• GIORGIO IERVASI (Unità di personale interno)
• ANNALISA IERVASI (Unità di personale interno)
• GIANCARLO ZUCCHELLI (Unità di personale interno)

Insieme di parole chiave di

• Parole chiave di "Serum thyroglobulin mesurement in the follow-up of patients treated for differentiated thyroid cancer" (Insieme di parole chiave)