Baseline characteristics of patients recruited in the AREA IN-CHF study (Antiremodelling Effect of Aldosterone Receptors Blockade with Canrenone in Mild Chronic Heart Failure) (Articolo in rivista)

Type
Label
  • Baseline characteristics of patients recruited in the AREA IN-CHF study (Antiremodelling Effect of Aldosterone Receptors Blockade with Canrenone in Mild Chronic Heart Failure) (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Alternative label
  • Boccanelli A.; Cacciatore G.; Mureddu G.; De Simone G.; Clemenza F.; De Maria R.; Di Lenarda A.; Gavazzi A. (2007)
    Baseline characteristics of patients recruited in the AREA IN-CHF study (Antiremodelling Effect of Aldosterone Receptors Blockade with Canrenone in Mild Chronic Heart Failure)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Boccanelli A.; Cacciatore G.; Mureddu G.; De Simone G.; Clemenza F.; De Maria R.; Di Lenarda A.; Gavazzi A. (literal)
Pagina inizio
  • 683 (literal)
Pagina fine
  • 691 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 8 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
  • In: Journal of Cardiovascular Medicine, vol. 8 pp. 683 - 691. Lippincott William & Wilkins, 2007. (literal)
Titolo
  • Baseline characteristics of patients recruited in the AREA IN-CHF study (Antiremodelling Effect of Aldosterone Receptors Blockade with Canrenone in Mild Chronic Heart Failure) (literal)
Abstract
  • Objective Excess aldosterone activity contributes to the pathogenesis and progression of heart failure (HF). Aldosterone antagonists improve clinical outcome in patients with severe HF or left ventricular (LV) dysfunction after myocardial infarction, but knowledge of their impact in mild chronic HF is sparse. AREA IN-CHF was planned to investigate the effects of canrenone on progression of LV remodelling in mild HF.Methods AREA IN-CHF is a multicentre, randomised, double-blind, parallel group comparison of canrenone (up to 50 mg/day) versus placebo in mild stable HF. The primary endpoint is change in echocardiographic LV end-diastolic volume over 12 months. Patients had New York Heart Association class II HF, LV ejection fraction (literal)
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