Extinction partially reverts structural changes associated with remote fear memory (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Extinction partially reverts structural changes associated with remote fear memory (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Alternative label

• Vetere G.1,2, Restivo L.1,3, Novembre G.1, Aceti M.2,4, Lumaca M.1, Ammassari-Teule M.1,2 (2011)
  Extinction partially reverts structural changes associated with remote fear memory
  in Learning & memory (Cold Spring Harbor N.Y.)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Vetere G.1,2, Restivo L.1,3, Novembre G.1, Aceti M.2,4, Lumaca M.1, Ammassari-Teule M.1,2 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• 554-7. doi: 10.1101/lm.2246711 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 18(9) (literal)

Rivista

• Learning & memory (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1 - Cell Biology and Neurobiology Institute, C.N.R.-National Research Council of Italy, 00143 Rome, Italy. 2- IRCCS Santa Lucia Foundation, 00143 Rome, Italy. Footnotes : Present addresses: 3 - Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada; 4 - Neuroscience Department, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA. (literal)

Titolo

• Extinction partially reverts structural changes associated with remote fear memory (literal)

Abstract

• Structural synaptic changes occur in medial prefrontal cortex circuits during remote memory formation. Whether extinction reverts or further reshapes these circuits is, however, unknown. Here we show that the number and the size of spines were enhanced in anterior cingulate (aCC) and infralimbic (ILC) cortices 36 d following contextual fear conditioning. Upon extinction, aCC spine density returned to baseline, but the enhanced proportion of large spines did not. Differently, ILC spine density remained elevated, but the size of spines decreased dramatically. Thus, extinction partially erases the remote memory network, suggesting that the preserved network properties might sustain reactivation of extinguished conditioned fear. (literal)

Prodotto di

• ex ME.P05.007.001 / Modelli animali per lo studio del sistema nervoso (ME.P05.007.002) (Modulo)

Autore CNR

• GISELLA VETERE (Persona)
• LEONARDO RESTIVO (Unità di personale esterno)
• ANNE MARIE TEULE (Persona)

Incoming links:

Autore CNR di

• ANNE MARIE TEULE (Persona)
• GISELLA VETERE (Persona)
• LEONARDO RESTIVO (Unità di personale esterno)

Prodotto

• ex ME.P05.007.001 / Modelli animali per lo studio del sistema nervoso (ME.P05.007.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Learning & memory (Rivista)