Helicobacter pylori therapy in children: A focus on proton pump inhibitors (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Helicobacter pylori therapy in children: A focus on proton pump inhibitors (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1159/000323619 (literal)

Alternative label

• Claudio Chiesa, Caterina Anania, Lucia Pacifico, Giuseppe Olivero, John F.Osborn. (2011)
  Helicobacter pylori therapy in children: A focus on proton pump inhibitors
  in Chemotherapy (Basel); Karger, Basel (Swaziland)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Claudio Chiesa, Caterina Anania, Lucia Pacifico, Giuseppe Olivero, John F.Osborn. (literal)

Pagina inizio

• 85 (literal)

Pagina fine

• 93 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 57 (literal)

Rivista

• Chemotherapy (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 9 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 1 (literal)

Note

• PubMe (literal)
• Scopu (literal)
• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1.Claudio Chiesa: Institute of Translational Pharmacology,National Research Council,Italy 2. Caterina Anania, Lucia Pacifico:Department of Pediatrics,Sapienza University of Rome,Italy 3. Giuseppe Olivero:Scientific Committee of the Italian Federation of Pediatricians, and Health Local Unit 'RM B', Rome , Italy 4.John F.Osborn:Department of Public Health Sciences and Infectious Diseases,Sapienza University of Rome,Rome,Italy (literal)

Titolo

• Helicobacter pylori therapy in children: A focus on proton pump inhibitors (literal)

Abstract

• Over the last two decades, there have been many studies on children who have sought an effective and safe treatment to eradicate Helicobacter pylori infection, but as yet, no therapy regimen has been found which is always effective and safe. Differences in drug response among pediatric patients are common. Such individual variability in drug response is multifactorial, including environmental, genetic, development and disease determinants that affect the disposition of a given drug. In pediatric efficacy studies for the management of H. pylori eradication in children, the most commonly tested regimen has contained a combination of proton pump inhibitor (PPI), clarithromycin and amoxicillin, followed by triple therapies containing PPI, clarithromycin and nitroimidazoles. Thus, PPIs are an integral part of triple therapy for H. pylori eradication in children with gastroduodenal disease. In this article, we comprehensively review, from a pediatric point of view, the literature on the clinical, pharmacologic and microbiologic properties of PPIs. We also discuss genetic, developmental and other host-related factors that may affect the efficacy of these drugs. Finally, we provide some guidance regarding their potential role and limitations for H. pylori eradication in children. (literal)

Editore

• Karger (Editore)

Prodotto di

• Ricerca traslazionale ed outcome nelle patologie infiammatorie e degenerative (ME.P04.009.001) (Modulo)

Autore CNR

• CLAUDIO CHIESA (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Helicobacter pylori therapy in children: A focus on proton pump inhibitors" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• CLAUDIO CHIESA (Unità di personale interno)

Prodotto

• Ricerca traslazionale ed outcome nelle patologie infiammatorie e degenerative (ME.P04.009.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Chemotherapy (Rivista)

Editore di

• Karger (Editore)

Insieme di parole chiave di

• Keywords of "Helicobacter pylori therapy in children: A focus on proton pump inhibitors" (Insieme di parole chiave)