ORTom: a multi-species approach based on conserved co-expression to identify putative functional relationships among genes in tomato. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• ORTom: a multi-species approach based on conserved co-expression to identify putative functional relationships among genes in tomato. (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1007/s11103-010-9638-z (literal)

Alternative label

• Miozzi, L., Provero, P., Accotto, G.P. (2010)
  ORTom: a multi-species approach based on conserved co-expression to identify putative functional relationships among genes in tomato.
  in Plant molecular biology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Miozzi, L., Provero, P., Accotto, G.P. (literal)

Pagina inizio

• 519 (literal)

Pagina fine

• 532 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• L'articolo è associato ad un database consultabile on line all'indirizzo web http://ortom.ivv.cnr.it/ Il lavoro è stato in parte supportato dai progetti ''GenoPom'' (MIUR, Italy), B74 (Ricerca Scientifica Applicata 2004, Regione Piemonte, Italy) e dall'Associazione Italiana per la Ricerca sul Cancro (AIRC). (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.springerlink.com/content/57214132457800j6/?MUD=MP (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 73 (literal)

Rivista

• Plant molecular biology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• DOI 10.1007/s11103-010-9638-z IMPACT FACTOR: 3.541 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 4-5 (literal)

Note

• ISI Web of Science (WOS) (literal)
• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• ML, AGP Istituto di Virologia Vegetale, CNR, Strada delle Cacce 73, 10135 Turin, Italy PP Molecular Biotechnology Center and Dipartimento di Genetica, Biologia e Biochimica, Universita` di Torino, Via Nizza 52, 10100 Turin, Italy (literal)

Titolo

• ORTom: a multi-species approach based on conserved co-expression to identify putative functional relationships among genes in tomato. (literal)

Abstract

• Co-expressed genes are often expected to be functionally related and many bioinformatics approaches based on co-expression have been developed to infer their biological role. However, such annotations may be unreliable, whereas the evolutionary conservation of gene co-expression among species may form a basis for more confident predictions. The huge amount of expression data (microarrays, SAGE, ESTs) has already allowed functional studies based on conserved co-expression in animals. Up to now, the implementation of analogous tools for plants has been strongly limited probably by the paucity and heterogeneity of data. Here we present ORTom, a tomato-centred EST data-mining approach based on conserved co-expression in the Solanaceae family. ORTom can be used to predict functional relationships among genes and to prioritize candidate genes for targeted studies. The method consists in ranking ESTs co-expressed with a gene of interest according to the level of expression pattern conservation in phylogenetically-related plants (potato, tobacco and pepper) to obtain lists of putative functionally-related genes. The lists are then analyzed for Gene Ontology keyword enrichment. The web server ORTom has been implemented to make the results publicly-available and searchable. Few biological examples on how the tool can be used are presented. (literal)

Prodotto di

• Interazioni biologiche e molecolari delle piante con virus e agenti patogeni virus-simili (AG.P01.010.001) (Modulo)

Autore CNR

• LAURA MIOZZI (Unità di personale interno)
• GIAN PAOLO ACCOTTO (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "ORTom: a multi-species approach based on conserved co-expression to identify putative functional relationships among genes in tomato." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• GIAN PAOLO ACCOTTO (Unità di personale interno)
• LAURA MIOZZI (Unità di personale interno)

Prodotto

• Interazioni biologiche e molecolari delle piante con virus e agenti patogeni virus-simili (AG.P01.010.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Plant molecular biology (Rivista)

Insieme di parole chiave di

• Parole chiave di "ORTom: a multi-species approach based on conserved co-expression to identify putative functional relationships among genes in tomato." (Insieme di parole chiave)