Lineage Specificity of the Evolutionary Dynamics of the mtdna D-Loop Region in Rodents (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Lineage Specificity of the Evolutionary Dynamics of the mtdna D-Loop Region in Rodents (Articolo in rivista) (literal)

Anno

• 2002-01-01T00:00:00+01:00 (literal)

Alternative label

• Larizza A., Pesole G., Reyes A., Sbisa' E., Saccone C. (2002)
  Lineage Specificity of the Evolutionary Dynamics of the mtdna D-Loop Region in Rodents
  in Journal of molecular evolution
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Larizza A., Pesole G., Reyes A., Sbisa' E., Saccone C. (literal)

Pagina inizio

• 145 (literal)

Pagina fine

• 155 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 54 (literal)

Rivista

• Journal of molecular evolution (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• Lineage Specificity of the Evolutionary Dynamics of the mtdna D-Loop Region in Rodents (literal)

Abstract

• This paper reports an intraorder study on the D-loop-containing region of the mitochondrial DNA in rodents. A complete multialignment of this region is not feasible with the exception of some conserved regions. The comparative analysis of 25 complete rodent sequences from 23 species plus one lagomorph has revealed that only the central domain (CD), a conserved region of about 80 bp in the extended termination-associated sequences (ETAS) domain, adjacent to the CD, the ETAS1, and conserved sequence block (CSB) 1 blocks are present in all rodent species, whereas the presence of CSB2 and CSB3 is erratic within the order. We have also found a conserved region of 90 bp located between tRNAPro and ETAS1 present in fat dormouse, squirrel, guinea pig, and rabbit. Repeated sequences are present in both the ETAS and the CSB domain, but the repeats differ in length, copy number, and base composition in different species. The potential use of the D-loop for evolutionary studies has been investigated; the presence/absence of conserved blocks and/or repeated sequences cannot be used as a reliable phylogenetic marker, since in some cases they may be shared by distantly related organisms but not by close ones, while in other ones a relationship between tree topology and presence/absence of such motifs is observed. Better results can be obtained by the use of the CD, which, however, due to its reduced size, when used for tracing a phylogenetic tree, shows some nodes with low statistical support (literal)

Autore CNR

• ELISABETTA SBISA' (Unità di personale interno)
• AURELIO FERNANDO REYES TELLEZ (Unità di personale interno)

Incoming links:

Autore CNR di

• ELISABETTA SBISA' (Unità di personale interno)
• AURELIO FERNANDO REYES TELLEZ (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of molecular evolution (Rivista)