http://www.cnr.it/ontology/cnr/individuo/prodotto/ID54851
Membrane bioreactor for cell tissues and organoids (Articolo in rivista)
- Type
- Label
- Membrane bioreactor for cell tissues and organoids (Articolo in rivista) (literal)
- Anno
- 2006-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1111/j.1525-1594.2006.00302.x (literal)
- Alternative label
Drioli, E., De Bartolo, L. (2006)
Membrane bioreactor for cell tissues and organoids
in Artificial organs
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Drioli, E., De Bartolo, L. (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- *Institute on Membrane Technology, National Research Council of Italy, ITM-CNR; and +Department of Chemical
Engineering, University of Calabria, Rende (CS), Italy (literal)
- Titolo
- Membrane bioreactor for cell tissues and organoids (literal)
- Abstract
- Progresses in polymeric membrane preparation
and in the understanding and control of their transport
properties make possible the design of novel membranes to
be used for cell culture (e.g., hepatocytes, lymphocytes, pancreatic
islets) in biohybrid systems such as therapeutic
device or as in vitro model systems for studying the effects
of various drugs and chemicals on cell metabolism. Special
attention is paid to the design of the membrane with
defined microstructure and physicochemical properties as
well as to the importance of transport and physicochemical
properties of the membrane in contact with the cells. The
development of new biomaterials and bioreactors able to
activate a specific response of the cells and to maintain cell
differentiation for a long time is one of the most pertinent
issues in the field of tissue engineering and regenerative
medicine. Polymeric membranes are attractive for their
selectivity and biostability characteristics in the use of biohybrid
systems for cell culture. Semipermeable membranes
act as a support for the adhesion of anchorage-dependent
cells and allow the specific transport of metabolites and
nutrients to cells and the removal of catabolites and specific
products. Moreover, new membrane systems that have
been recently realized as the membrane contactors might
also potentially contribute to regenerative medicine and
tissue engineering. (literal)
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- Autore CNR
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