DNA adsorption measured with ultra-thin film organic field effect transistors (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• DNA adsorption measured with ultra-thin film organic field effect transistors (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.bios.2009.02.003 (literal)

Alternative label

• P. Stoliar (1), E. Bystrenova (1), S. D. Quiroga (1), P. Annibale (1), M. Facchini (1), M. Spijkman (2), S. Setayesh (2), D. de Leeuw (2) and F. Biscarini (1) (2009)
  DNA adsorption measured with ultra-thin film organic field effect transistors
  in Biosensors & bioelectronics
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• P. Stoliar (1), E. Bystrenova (1), S. D. Quiroga (1), P. Annibale (1), M. Facchini (1), M. Spijkman (2), S. Setayesh (2), D. de Leeuw (2) and F. Biscarini (1) (literal)

Pagina inizio

• 2935 (literal)

Pagina fine

• 2938 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 24 (literal)

Rivista

• Biosensors & bioelectronics (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 4 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 9 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1. CNR, Ist Studio Mat Nanostrutturati, I-40129 Bologna, Italy 2. Philips Res High Tech Campus 4 WAG1 234, NL-5656 AE Eindhoven, Netherlands (literal)

Titolo

• DNA adsorption measured with ultra-thin film organic field effect transistors (literal)

Abstract

• Organic ultra-thin film field effect transistors (FET) are operated as label-free sensors of deoxyribonucleic acid (DNA) adsorption. Linearized plasmid DNA molecules (4361 base pairs) are deposited from a solution on two monolayers thick pentacene FET. The amount of adsorbed DNA is measured by AFM and correlated to the concentration of the solution. Electrical characteristics on the dried DNA/pentacene FETs were studied as a function of DNA concentration in the solution. Shift of the pinch-off voltage across a wide range of DNA concentration, from very diluted to highly concentrated, is observed. It can be ascribed to additional positive charges in the semiconductor induced by DNA at a rate of one charge for every 200 base pairs. The sensitivity 74ng/cm2, corresponding to 650ng/ml, is limited by the distribution of FET parameters upon repeated cycles, and is subjected to substantial improvement upon standardization. Our work demonstrates the possibility to develop label-free transducers suitable to operate in regimes of high molecular entanglement. (literal)

Prodotto di

• Nanotecnologie di materiali multifunzionali e sistemi biologici (PM.P05.010.001) (Modulo)
• Istituto per lo studio dei materiali nanostrutturati (ISMN) (Istituto)

Autore CNR

• PABLO ALBERTO STOLIAR (Unità di personale interno)
• EVA BYSTRENOVA (Persona)
• Santiago David Quiroga (Persona)
• PAOLO ANNIBALE (Persona)
• FABIO BISCARINI (Unità di personale interno)
• MASSIMO FACCHINI (Persona)

Insieme di parole chiave

• Parole chiave di "DNA adsorption measured with ultra-thin film organic field effect transistors" (Insieme di parole chiave)

Incoming links:

Prodotto

• Istituto per lo studio dei materiali nanostrutturati (ISMN) (Istituto)
• Nanotecnologie di materiali multifunzionali e sistemi biologici (PM.P05.010.001) (Modulo)

Autore CNR di

• Santiago David Quiroga (Persona)
• PAOLO ANNIBALE (Persona)
• MASSIMO FACCHINI (Persona)
• PABLO ALBERTO STOLIAR (Unità di personale interno)
• FABIO BISCARINI (Unità di personale interno)
• EVA BYSTRENOVA (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Biosensors & bioelectronics (Rivista)

Insieme di parole chiave di

• Parole chiave di "DNA adsorption measured with ultra-thin film organic field effect transistors" (Insieme di parole chiave)