Reaction of hydrogen atom with Met-enkephalin and related peptides (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Reaction of hydrogen atom with Met-enkephalin and related peptides (Articolo in rivista) (literal)

Anno

• 2006-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1002/chem.200600828 (literal)

Alternative label

• Mozziconacci, O.; Bobrowski, K.; Ferreri, C.; Chatgilialoglu, C. (2006)
  Reaction of hydrogen atom with Met-enkephalin and related peptides
  in Chemistry (Weinh., Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Mozziconacci, O.; Bobrowski, K.; Ferreri, C.; Chatgilialoglu, C. (literal)

Pagina inizio

• 2029 (literal)

Pagina fine

• 2033 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 13 (literal)

Rivista

• Chemistry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• published on line - November 24, 2006 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 5 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 7 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• ISOF e Institute of Nuclear Chemistry and Technology Department of Radiation Chemistry and Technology Dorodna 16, 03-195 Warsaw, Poland (literal)

Titolo

• Reaction of hydrogen atom with Met-enkephalin and related peptides (literal)

Abstract

• The reactions of hydrogen atoms with enkephalins and related peptides have been investigated by radiolytic methods in aqueous solutions and lipid vesicle suspensions. Pulse radiolysis experiments indicate that methionine residue (Met)is the main target. In Met-enkephalin (Tyr-Gly- Gly-Phe-Met)the attack of the hydrogen atom occurs to about 50% on Met with formation of methanethiyl radical. The remaining percentage is divided roughly evenly between Tyr and Phe. With Leu-enkephalin (Tyr-Gly-Gly- Phe-Leu)the site of attack is limited to Tyr and Phe. Using a peptide-liposome (that is, 1-palmitoyl-2-oleoyl phosphatidylcholine vesicles)model, the cis- trans isomerization of phospholipids could be detected due to the catalytic action of thiyl radicals. The radiation chemical yields of the HC and, consequently of CH3SC radical, was modulated by the experimental conditions and the nature of peptide. Large amounts of trans lipids observed in phosphate buffer vesicle suspensions indicated the efficient role of double-bond isomerization as marker of Met-containing peptide damage. (literal)

Prodotto di

• Institute for organic syntheses and photoreactivity (ISOF) (Istituto)
• Modelli biomimetici di stress radicalico e biomarcatori correlati (PM.P06.006.001) (Modulo)

Autore CNR

• CARLA FERRERI (Unità di personale interno)
• CHRYSSOSTOMOS CHATGILIALOGLU (Unità di personale interno)
• OLIVIER MOZZICONACCI (Persona)

Incoming links:

Prodotto

• Institute for organic syntheses and photoreactivity (ISOF) (Istituto)
• Modelli biomimetici di stress radicalico e biomarcatori correlati (PM.P06.006.001) (Modulo)

Autore CNR di

• CARLA FERRERI (Unità di personale interno)
• CHRYSSOSTOMOS CHATGILIALOGLU (Unità di personale interno)
• OLIVIER MOZZICONACCI (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Chemistry (Rivista)