Increased risk of depressive and anxiety disorders in relatives of patients with Parkinson disease (Articolo in rivista)

Type
Label
  • Increased risk of depressive and anxiety disorders in relatives of patients with Parkinson disease (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Alternative label
  • Arabia, G., Grossardt, B.R., Geda, Y.E., Carlin, J.M., Boer, J.H., Ahlskog, J.E., Maraganore, D.M., Rocca, W.A (2007)
    Increased risk of depressive and anxiety disorders in relatives of patients with Parkinson disease
    in Archives of general psychiatry
    (literal)
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  • Arabia, G., Grossardt, B.R., Geda, Y.E., Carlin, J.M., Boer, J.H., Ahlskog, J.E., Maraganore, D.M., Rocca, W.A (literal)
Pagina inizio
  • 1385 (literal)
Pagina fine
  • 1392 (literal)
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  • 64(12 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
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  • Department of Health Sciences Research, Divisions of Epidemiology (Drs Arabia, Geda, and Rocca) and Biostatistics (Messrs Grossardt and Carlin), Department of Psychiatry and Psychology (Dr Geda), and Department of Neurology (Drs Bower, Ahlskog, Maraganore, and Rocca), Mayo Clinic College of Medicine, Rochester, Minnesota. Dr Arabia was on leave from the Institute of Neurological Sciences, Italian National Research Council, Cosenza, Italy, at the time of the study (literal)
Titolo
  • Increased risk of depressive and anxiety disorders in relatives of patients with Parkinson disease (literal)
Abstract
  • CONTEXT: Relatives of patients with Parkinson disease (PD) have an increased risk of PD and other neurologic disorders; however, their risk of psychiatric disorders remains uncertain. OBJECTIVE: To study the risk of depressive disorders and anxiety disorders among first-degree relatives of patients with PD compared with first-degree relatives of controls. DESIGN, SETTING, AND PARTICIPANTS: In a population-based, historical cohort study, we included 1000 first-degree relatives of 162 patients with PD and 850 first-degree relatives of 147 controls. Both patients with PD and controls were representative of the population of Olmsted County, Minnesota. MAIN OUTCOME MEASURES: Documentation of psychiatric disorders was obtained for each relative separately through a combination of telephone interviews with the relatives (or their proxies) and review of their medical records from a records-linkage system (family study method). Psychiatric disorders were defined using clinical criteria from the DSM-IV or routine diagnoses. RESULTS: We found an increased risk of several psychiatric disorders in first-degree relatives of patients with PD compared with first-degree relatives of controls (hazar (literal)
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