Apolipoprotein E genotype does not influence the progression of multiple sclerosis. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Apolipoprotein E genotype does not influence the progression of multiple sclerosis. (Articolo in rivista) (literal)

Anno

• 2003-01-01T00:00:00+01:00 (literal)

Alternative label

• Savettieri G1,Andreoli V2, Bonavita S3, Cittadella R2, Caltagirone C4, Fazio MC5, Girlanda P5, Le Pira F6, Liguori M7, Logroscino G8, Lugaresi A9,Nocentini U4, Reggio A6,Salemi G1, Serra P2,Tedeschi G3,Toma L9,Trojano M7,Valentino P10,Quattrone A.2-10 (2003)
  Apolipoprotein E genotype does not influence the progression of multiple sclerosis.
  in Journal of neurology (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Savettieri G1,Andreoli V2, Bonavita S3, Cittadella R2, Caltagirone C4, Fazio MC5, Girlanda P5, Le Pira F6, Liguori M7, Logroscino G8, Lugaresi A9,Nocentini U4, Reggio A6,Salemi G1, Serra P2,Tedeschi G3,Toma L9,Trojano M7,Valentino P10,Quattrone A.2-10 (literal)

Pagina inizio

• 1094 (literal)

Pagina fine

• 1098 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 250 (literal)

Rivista

• Journal of neurology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• Apolipoprotein E genotype does not influence the progression of multiple sclerosis. (literal)

Abstract

• OBJECTIVE: To investigate the association between apolipoprotein E (APOE) polymorphisms and the progression of MS. METHODS: We investigated 428 subjects affected by clinically defined MS, with a disease duration of at least three years. We collected data concerning the age at onset of MS, clinical type, disease duration and disability according to the expanded disability status scale (EDSS). We also calculated the progression index (PI) to evaluate disease progression. APOE genotyping and the -491 A/T polymorphism of the APOE promoter were determined. RESULTS: No association was observed between the APOE epsilon4 allele and clinical characteristics of our study population. We also investigated the -491 A/T APOE promoter polymorphism in 236 MS subjects and did not find any association between the -491 A/T polymorphism and the selected clinical variables. CONCLUSIONS: In our population the APOE epsilon4 allele and the -491 A/T APOE promoter polymorphism are not associated with a more rapid course of MS. (literal)

Prodotto di

• Genetica delle malattie multifattoriali (ME.P02.012.002) (Modulo)
• Institute of neurological sciences (ISN) (Istituto)

Autore CNR

• MARIA LIGUORI (Unità di personale interno)
• VIRGINIA ANDREOLI (Unità di personale interno)
• RITA CITTADELLA (Persona)

Incoming links:

Autore CNR di

• RITA CITTADELLA (Persona)
• VIRGINIA ANDREOLI (Unità di personale interno)
• MARIA LIGUORI (Unità di personale interno)

Prodotto

• Institute of neurological sciences (ISN) (Istituto)
• Genetica delle malattie multifattoriali (ME.P02.012.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of neurology (Rivista)