The Germinal centre-derived lymphomas seen through their cellular microenvironment (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• The Germinal centre-derived lymphomas seen through their cellular microenvironment (Articolo in rivista) (literal)

Anno

• 2009-01-01T00:00:00+01:00 (literal)

Alternative label

• Carbone A. 1, Gloghini A. 1, Cabras A. 1, Elia G. 2 (2009)
  The Germinal centre-derived lymphomas seen through their cellular microenvironment
  in British journal of haematology (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Carbone A. 1, Gloghini A. 1, Cabras A. 1, Elia G. 2 (literal)

Pagina inizio

• 468 (literal)

Pagina fine

• 480 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni

• Epub 2008 Mar 5 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 145/4 (literal)

Rivista

• British journal of haematology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1 - Department of Pathology and Laboratory and Transfusion Medicine, Istituto Nazionale Tumori, Milano, Italy; 2 - Mass Spectrometry Resource, Conway Institute for Biomolecular and Biomedical Research, University College Dublin Belfield, Dublin, Ireland (literal)

Titolo

• The Germinal centre-derived lymphomas seen through their cellular microenvironment (literal)

Abstract

• The human lymph node is a complex tissue resulting from the microenvironmental organisation of different cell populations linked by topographical and/or functional relationships. Germinal centres (GCs) of lymphoid follicles contain a meshwork of follicular dendritic cells in addition to B-cells and some CD4(+) T cells. Moreover, there is a sharp demarcation around the whole follicle centre, which is highlighted by fibroblastic reticulum cells. On the whole, GC exerts a role in B cell physiology and malignancy. In GC-derived lymphomas, gene expression profiling studies have raised the possibility that survival of the affected patients may be associated with signatures preferentially expressed in non-malignant T cells and macrophages and/or dendritic cells. Immunohistological analyses in lymphoma biopsy samples have confirmed that the biological behaviour and tumour progression may be influenced by the tumour microenvironment. This review will examine GC-derived lymphomas, including follicular lymphomas, Hodgkin lymphomas and angioimmunoblastic T-cell lymphoma, through their integrated cellular microenvironment, highlighting those findings which may serve as a useful surrogate marker for tumour diagnosis or tumour progression, together with key molecules involved in tumour development. (literal)

Prodotto di

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Ormonogenesi e differenziamento tiroideo.Patogenesi delle atassie cerebellari da canalopatie e poliglutammine espanse (ME.P05.008.001) (Modulo)

Autore CNR

• GIULIANO ELIA (Unità di personale interno)

Insieme di parole chiave

• Keywords of "The Germinal centre-derived lymphomas seen through their cellular microenvironment" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• GIULIANO ELIA (Unità di personale interno)

Prodotto

• Istituto di neurobiologia e medicina molecolare (INMM) (Istituto)
• Ormonogenesi e differenziamento tiroideo.Patogenesi delle atassie cerebellari da canalopatie e poliglutammine espanse (ME.P05.008.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• British journal of haematology (Rivista)

Insieme di parole chiave di

• Keywords of "The Germinal centre-derived lymphomas seen through their cellular microenvironment" (Insieme di parole chiave)