New technologies used in the study of human melanoma (Articolo in rivista)

Type
Label
  • New technologies used in the study of human melanoma (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/S0074-7696(07)61006-7 (literal)
Alternative label
  • Felsani Armando 1; Mileo Anna Maria 2; Maresca Vittoria 2; Picardo Mauro 2; Paggi Marco G. 2 (2007)
    New technologies used in the study of human melanoma
    in International review of cytology
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Felsani Armando 1; Mileo Anna Maria 2; Maresca Vittoria 2; Picardo Mauro 2; Paggi Marco G. 2 (literal)
Pagina inizio
  • 247 (literal)
Pagina fine
  • 286 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://www.sciencedirect.com/science/article/pii/S0074769607610067 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 261 (literal)
Rivista
Note
  • PubMe (literal)
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1 CNR, Istituto di Neurobiologia e Medicina Molecolare, 00143 Rome, Italy 2 Regina Elena Cancer Institute, 00158 Rome, Italy 3 San Gallicano Dermatological Institute, 00153 Rome, Italy (literal)
Titolo
  • New technologies used in the study of human melanoma (literal)
Abstract
  • The amount of information on tumor biology has expanded enormously, essentially due to the completion of the human genome sequencing and to the application of new technologies that represent an exciting breakthrough in molecular analysis. Often these data spring from experimental procedures, such as a serial analysis of gene expression (SAGE) and DNA microarrays, which cannot be defined as hypothesis-driven: it may appear to be a \"brute force\" approach through which no information can be directly generated concerning the specific functions of selected genes in a definite context. However, interesting results are fruitfully generated, and thus it is important to consider the enormous potential these new technologies possess and to learn how to apply this novel form of knowledge in the emerging field of molecular medicine. This review, after a limited outline regarding several classic aspects of human cutaneous melanoma biology, genetics, and clinical approaches, will focus on the proficient use of up-to-date technologies in the study of the neoplastic disease and on their capability to provide effective support to conventional approaches in melanoma diagnosis, prognosis, and treatment. (literal)
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