99mTc-HMPAO distribution at SPECT is associated with succinate-cytochrome c reductase (SCR) activity in subjects with psychiatric disorders (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• 99mTc-HMPAO distribution at SPECT is associated with succinate-cytochrome c reductase (SCR) activity in subjects with psychiatric disorders (Articolo in rivista) (literal)

Anno

• 2004-01-01T00:00:00+01:00 (literal)

Alternative label

• Gardner A., Pagani M., Beier, H., Larsson, S.A., Hallstrom, T. (2004)
  99mTc-HMPAO distribution at SPECT is associated with succinate-cytochrome c reductase (SCR) activity in subjects with psychiatric disorders
  in Nuclear medicine and biology; Elsevier Inc., San Diego (Stati Uniti d'America)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Gardner A., Pagani M., Beier, H., Larsson, S.A., Hallstrom, T. (literal)

Pagina inizio

• 277 (literal)

Pagina fine

• 282 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 31 (literal)

Rivista

• Nuclear medicine and biology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• NEUROTEC Department, Section of Psychiatry, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden Section for Nuclear Medicine, Department of Hospital Physics, Karolinska Hospital, Stockholm, Sweden Institute of Cognitive Sciences and Technology, CNR, Rome, Italy Child- and Adolescent Out-Patient Psychiatric Services, Kalmar Regional Hospital, Kalmar, formerly at Psychosis Care Unit, Ryhov Regional Hospital, Jonkoping, Sweden Department of Radiology, Karolinska Hospital, Stockholm, Sweden (literal)

Titolo

• 99mTc-HMPAO distribution at SPECT is associated with succinate-cytochrome c reductase (SCR) activity in subjects with psychiatric disorders (literal)

Abstract

• The origin of altered 99mTc-HMPAO distribution at SPECT in psychiatric disorders is unknown. Correlations between brain 99m Tc-HMPAO distribution and muscle succinate-cytochrome c reductase (SCR, complex II ? III) were assessed in 20 unmedicated psychiatric patients. Significant negative correlations were found between 99mTc-HMPAO distribution in associative sensory regions and SCR activity. Sensory cortices are normally enriched in complex II activity. The production of electrons and reactive oxygen species affecting the redox state is considered to be highest from complex III, but complex II may also contribute. The negative relationship between 99mTc-HMPAO uptake and SCR activity may be due to redox state alterations influencing fixation of the radiopharmaceutical. (literal)

Editore

• Elsevier Inc. (Editore)

Prodotto di

• Institute of cognitive sciences and technologies (ISTC) (Istituto)
• Neuropatologie e bisogni individuali: diagnostica per immagini, assessment linguistico-cognitivo, counseling genetico e trattamento riabilitativo (ME.P02.015.001) (Modulo)

Autore CNR

• MARCO PAGANI (Persona)

Insieme di parole chiave

• Parole chiave di "99mTc-HMPAO distribution at SPECT is associated with succinate-cytochrome c reductase (SCR) activity in subjects with psychiatric disorders" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARCO PAGANI (Persona)

Prodotto

• Institute of cognitive sciences and technologies (ISTC) (Istituto)
• Neuropatologie e bisogni individuali: diagnostica per immagini, assessment linguistico-cognitivo, counseling genetico e trattamento riabilitativo (ME.P02.015.001) (Modulo)

Editore di

• Elsevier Inc. (Editore)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Nuclear medicine and biology (Rivista)

Insieme di parole chiave di

• Parole chiave di "99mTc-HMPAO distribution at SPECT is associated with succinate-cytochrome c reductase (SCR) activity in subjects with psychiatric disorders" (Insieme di parole chiave)