Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes (Articolo in rivista)

Type
Label
  • Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes (Articolo in rivista) (literal)
Anno
  • 2006-01-01T00:00:00+01:00 (literal)
Alternative label
  • Marchetti, S; Onori, G; Cametti, C (2006)
    Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Marchetti, S; Onori, G; Cametti, C (literal)
Pagina inizio
  • 24761 (literal)
Pagina fine
  • 24765 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 110 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Univ Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy; INFM, CRS SOFT, Unit Roma 1, CEMIN, Rome, Italy; Univ Perugia, Dipartimento Fis, I-06100 Perugia, Italy; Univ Florence, Dipartimento Fis, I-50019 Florence, Italy (literal)
Titolo
  • Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes (literal)
Abstract
  • By means of combined calorimetric and dynamic light-scattering measurements, we have investigated the conformational behavior of DNA chains after thermal melting in the presence of a cationic surfactant at different concentrations, up to a surfactant-to-phosphate group molar ratio close to unity. Both the specific heat capacity, C P ex, and the hydrodynamic radius R of the DNA chains provide support for the existence of two structural arrangements with different thermal stabilities, coexisting in the bulk solution. Although a component remains an elongated unfolded DNA chain originated in the thermal denaturation, the second component, consisting of DNA-surfactant complexes, assumes a compact structure with an average size of about 80 nm, whose thermal denaturation occurs at temperatures higher than 100 degrees C. (literal)
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