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Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes (Articolo in rivista)
- Type
- Label
- Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes (Articolo in rivista) (literal)
- Anno
- 2006-01-01T00:00:00+01:00 (literal)
- Alternative label
Marchetti, S; Onori, G; Cametti, C (2006)
Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes
(literal)
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- Marchetti, S; Onori, G; Cametti, C (literal)
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- Pagina fine
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- Note
- ISI Web of Science (WOS) (literal)
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- Univ Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy; INFM, CRS SOFT, Unit Roma 1, CEMIN, Rome, Italy; Univ Perugia, Dipartimento Fis, I-06100 Perugia, Italy; Univ Florence, Dipartimento Fis, I-50019 Florence, Italy (literal)
- Titolo
- Calorimetric and dynamic light-scattering investigation of cationic surfactant-DNA complexes (literal)
- Abstract
- By means of combined calorimetric and dynamic light-scattering measurements, we have investigated the conformational behavior of DNA chains after thermal melting in the presence of a cationic surfactant at different concentrations, up to a surfactant-to-phosphate group molar ratio close to unity. Both the specific heat capacity, C P ex, and the hydrodynamic radius R of the DNA chains provide support for the existence of two structural arrangements with different thermal stabilities, coexisting in the bulk solution. Although a component remains an elongated unfolded DNA chain originated in the thermal denaturation, the second component, consisting of DNA-surfactant complexes, assumes a compact structure with an average size of about 80 nm, whose thermal denaturation occurs at temperatures higher than 100 degrees C. (literal)
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