Supercritical CO2-extracted tomato oleoresins enhance gap junction intercellular communications and recover from mercury chloride inhibition in keratinocytes. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Supercritical CO2-extracted tomato oleoresins enhance gap junction intercellular communications and recover from mercury chloride inhibition in keratinocytes. (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1021/jf1001765 (literal)

Alternative label

• Leone A; Zefferino R; Longo C; Leo L; Zacheo G (2010)
  Supercritical CO2-extracted tomato oleoresins enhance gap junction intercellular communications and recover from mercury chloride inhibition in keratinocytes.
  in Journal of agricultural and food chemistry; ACS, American chemical society, Washington, DC (Stati Uniti d'America)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Leone A; Zefferino R; Longo C; Leo L; Zacheo G (literal)

Pagina inizio

• 4769 (literal)

Pagina fine

• 4778 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 58 (literal)

Rivista

• Journal of agricultural and food chemistry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• IF 2.562 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 9 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Leone A: National Research Council, Institute of Science of Food Production (CNR, ISPA), Lecce, Italy; Zefferino R:Department of Medical and Occupational Sciences, University of Foggia, Foggia, Italy (literal)

Titolo

• Supercritical CO2-extracted tomato oleoresins enhance gap junction intercellular communications and recover from mercury chloride inhibition in keratinocytes. (literal)

Abstract

• A nutritionally relevant phytochemical such as lycopene, found in tomatoes and other fruits, has been proposed to have health-promoting effects by modulating hormonal and immune systems, metabolic pathways, and gap junction intercellular communication (GJIC). This work analyzes lycopene extracts, obtained from tomato and tomato added with grape seeds by using a safe and environmentally friendly extraction process, based on supercritical carbon dioxide technology (S-CO2). Analysis of the innovative S-CO2-extracted oleoresins showed peculiar chemical composition with high lycopene concentration and the presence of other carotenoids, lipids, and phenol compounds. The oleoresins showed a higher in vitro antioxidant activity compared with pure lycopene and ²-carotene and the remarkable ability to enhance the GJIC and to increase cx43 expression in keratinocytes. The oleoresins, (0.9 ¼M lycopene), were also able to overcome, completely, the GJIC inhibition induced by 10 nM HgCl2, mercury(II) chloride, suggesting a possible action mechanism. (literal)

Editore

• ACS, American chemical society (Editore)

Prodotto di

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)
• Biotecnologie per la qualità e sicurezza degli alimenti (AG.P05.007.001) (Modulo)

Autore CNR

• ANTONELLA LEONE (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "Supercritical CO2-extracted tomato oleoresins enhance gap junction intercellular communications and recover from mercury chloride inhibition in keratinocytes." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANTONELLA LEONE (Unità di personale interno)

Prodotto

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)
• Biotecnologie per la qualità e sicurezza degli alimenti (AG.P05.007.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of agricultural and food chemistry (Rivista)

Editore di

• ACS, American chemical society (Editore)

Insieme di parole chiave di

• Parole chiave di "Supercritical CO2-extracted tomato oleoresins enhance gap junction intercellular communications and recover from mercury chloride inhibition in keratinocytes." (Insieme di parole chiave)