Contribution of voltage-gated potassium channels to the regulation of apoptosis. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Contribution of voltage-gated potassium channels to the regulation of apoptosis. (Articolo in rivista) (literal)

Anno

• 2010-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.febslet.2010.01.038 (literal)

Alternative label

• Szabò I; M. Zoratti; E. Gulbins (2010)
  Contribution of voltage-gated potassium channels to the regulation of apoptosis.
  in FEBS letters (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Szabò I; M. Zoratti; E. Gulbins (literal)

Pagina inizio

• 2049 (literal)

Pagina fine

• 2956 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/science/article/pii/S001457931000061X (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 584 (literal)

Rivista

• FEBS letters (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 8 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 10 (literal)

Note

• Scopu (literal)
• ISI Web of Science (WOS) (literal)
• PubMe (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Szabò I: Dip. di Biolgia, Università di Padova M. Zoratti: IN- Neuroscienze e Dip. di Scienze Biomediche Sperimentali, Università di Padova Gulbins E: Department of Molecular Biology, University of Duisburg-Essen, Germany (literal)

Titolo

• Contribution of voltage-gated potassium channels to the regulation of apoptosis. (literal)

Abstract

• Recent evidence points to the crucial involvement of voltage-gated potassium channels (Kv) in apoptotic volume decrease and in the regulation of apoptosis in several systems. We have recently described the presence of a Kv channel, Kv1.3, in the mitochondria of lymphocytes. Expression of the channel correlated with increased sensitivity to apoptotic stimuli. Mitochondrial Kv1.3 contributes to the apoptotic cascade in T lymphocytes by interacting with pro-apoptotic Bax resulting in alteration of mitochondrial functional parameters and ultimately, in cytochrome c release. The present review summarizes the current understanding of the function of Kv channels in apoptosis in several cell types as well as the role of mitochondrial Kv1.3 in the regulation of cell death in lymphocytes. (literal)

Prodotto di

• Neurobiologia e Neuropatologia (ME.P02.005.001) (Modulo)
• Istituto di neuroscienze (IN) (Istituto)

Autore CNR

• MARIO ZORATTI (Persona)

Insieme di parole chiave

• Keywords of "Contribution of voltage-gated potassium channels to the regulation of apoptosis." (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARIO ZORATTI (Persona)

Prodotto

• Istituto di neuroscienze (IN) (Istituto)
• Neurobiologia e Neuropatologia (ME.P02.005.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• FEBS letters (Rivista)

Insieme di parole chiave di

• Keywords of "Contribution of voltage-gated potassium channels to the regulation of apoptosis." (Insieme di parole chiave)