Reduced startle reflex and aversive noise perception in patients with orbitofrontal cortex lesions. (Articolo in rivista)

Type
Label
  • Reduced startle reflex and aversive noise perception in patients with orbitofrontal cortex lesions. (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1016/j.neuropsychologia.2007.10.018 (literal)
Alternative label
  • Angrilli A., Bianchin M., Radaelli S., Bertagnoni G., Pertile M. (2008)
    Reduced startle reflex and aversive noise perception in patients with orbitofrontal cortex lesions.
    in Neuropsychologia (Print); Pergamon-Elsevier Press Science LDT, Oxford (Regno Unito)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Angrilli A., Bianchin M., Radaelli S., Bertagnoni G., Pertile M. (literal)
Pagina inizio
  • 1179 (literal)
Pagina fine
  • 1184 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 46 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 6 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Department of General Psychology, University of Padova, Via Venezia 8, 35131 Padova, Italy CNR Institute of Neuroscience, Section of Padova, Italy Department of Neuroscience, San Bortolo Hospital, Vicenza, Italy Department of Mechanical Engineering, University of Padova, Italy (literal)
Titolo
  • Reduced startle reflex and aversive noise perception in patients with orbitofrontal cortex lesions. (literal)
Abstract
  • In the present study, the primary emotional response represented by the acoustic startle reflex was investigated in a group of six male patients, selected with lesions of the orbitofrontal cortex, and twenty matched healthy controls. Accurate neuropsychological assessment and lesion mapping showed relatively spared cognitive functioning in the patient group, most of the lesions being confined to the bilateral polar orbitofrontal cortex. Patients had significant inhibition of startle amplitude, together with a reduced self-evaluated perception of the unpleasantness of the acoustic probe stimulus. Results add to current literature on the circuit of the human startle reflex, by suggesting cortical-limbic down-regulation of the orbitofrontal cortex on the main startle pathway, probably at the level of the activating reticular system. The orbitofrontal cortex, together with the amygdala, is confirmed to represent the main center organizing both primary and secondary learned aspects of emotions. (literal)
Editore
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Editore di
Insieme di parole chiave di
data.CNR.it