Trends in incidence, risk factors, and survival in symptomatic lacunar stroke in Dijon, France, from 1989 to 2006: a population-based study. (Articolo in rivista)

Type
Label
  • Trends in incidence, risk factors, and survival in symptomatic lacunar stroke in Dijon, France, from 1989 to 2006: a population-based study. (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1161/STROKEAHA.107.510933 (literal)
Alternative label
  • Bejot Y; Catteau A; Caillier M; Rouaud O; Durier J; Marie C; Di Carlo A; Osseby GV; Moreau T; Giroud M. (2008)
    Trends in incidence, risk factors, and survival in symptomatic lacunar stroke in Dijon, France, from 1989 to 2006: a population-based study.
    in Stroke
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Bejot Y; Catteau A; Caillier M; Rouaud O; Durier J; Marie C; Di Carlo A; Osseby GV; Moreau T; Giroud M. (literal)
Pagina inizio
  • 1945 (literal)
Pagina fine
  • 1951 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://stroke.ahajournals.org/cgi/content/full/39/7/1945 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 39 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali
  • 7 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 7 (literal)
Note
  • PubMe (literal)
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • The Stroke Registry of Dijon (Inserm et Institut de Veille Sanitaire); University Hospital and Faculty of Medicine of Dijon, University of Burgundy, Dijon, France; the Laboratory of Pharmacodynamics, Inserm, University of Burgundy, Dijon, France; and the Department of Neurosciences, Firenze, Italy. (literal)
Titolo
  • Trends in incidence, risk factors, and survival in symptomatic lacunar stroke in Dijon, France, from 1989 to 2006: a population-based study. (literal)
Abstract
  • Background and Purpose--Lacunar infarcts are usually regarded as benign stroke, but population-based studies are required to assess the exact place of this stroke subtype in cerebrovascular pathology. Methods--We evaluated trends in incidence rates, risk factor profiles, and survival rates in symptomatic lacunar stroke from a prospective population-based registry from 1989 to 2006. Results--We recorded 2536 ischemic strokes. Among these, 715 (28%) were lacunar infarcts (354 men and 361 women). From 1989 to 2006, we observed a significant rise in the incidence of lacunar stroke in the 2 sexes considered together (relative risk, 1.02; 95% CI, 1.005 to 1.035; P?0.007), whereas the variation was not significant in either men or women when considered separately. Incidence rates significantly increased in young patients under 65 years old (relative risk, 1.049; 95% CI, 1.0175 to 1.0817; P?0.002). Concerning the distribution of cerebrovascular risk factors, lacunar stroke differed from nonlacunar stroke only with regard to the lower prevalence of a history of atrial fibrillation in the former (P?0.001). For lacunar infarcts, survival rates were 96% at 1 month (95% CI, 0.94 to 0.97), 86% at 1 year (95% CI, 0.83 to 0.89), and 78% at 2 years (95% CI, 0.75 to 0.81) and were significantly higher than those for nonlacunar stroke (hazard ratio, 2.05; 95% CI, 1.70 to 2.47; P?0.001). Conclusion--Our results suggest a significant increase in the incidence rates of lacunar stroke with a relatively good short-term prognosis in terms of survival. The association among hypertension, diabetes mellitus, and lacunar stroke was no stronger than the association between these 2 risk factors and nonlacunar stroke. ( (literal)
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