Esophagitis in frail elderly people. (Articolo in rivista)

Type
Label
  • Esophagitis in frail elderly people. (Articolo in rivista) (literal)
Anno
  • 2007-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1097/01.mcg.0000225611.48728.1e (literal)
Alternative label
  • Cardin F; Minicuci N; Siviero P; Bertolio S; Gasparini G; Inelmen E.M.; Terranova O. (2007)
    Esophagitis in frail elderly people.
    in Journal of clinical gastroenterology
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Cardin F; Minicuci N; Siviero P; Bertolio S; Gasparini G; Inelmen E.M.; Terranova O. (literal)
Pagina inizio
  • 257 (literal)
Pagina fine
  • 263 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 41 (literal)
Rivista
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Geriatric Department, Division of Geriatric Surgery / Geriatric Department, Geriatrics Division, University of Padova, Italy / CNR, Institute of Neuroscience, Padova, Italy. (literal)
Titolo
  • Esophagitis in frail elderly people. (literal)
Abstract
  • Introduction: We studied the clinical course of elderly patients acutely hospitalized for various diseases, assessing any differences between patients with and without esophagitis. Study: A case-control study on the presence of esophagitis was conducted on the clinical records of all in-patients undergoing gastroduodenoscopy at Padova Geriatric Hospital from 1997 to 2001. Data were examined on 338 sex-matched patients: 169 with a diagnosis of esophagitis and 169 with a negative endoscopy. Results: Admissions for acute respiratory disorders [odds ratios (OR) 2.68; 95% confidence interval (CI) 0.89-8.01], a remote diagnosis of esophagitis (OR 11.34; 95%CI 2.68-48.07), obesity (OR 3.36; 95%CI 0.91-12.48), and being bedridden (OR 6.84; 95%CI 3.27-14.29) were found to be independent risk factors for the presence of esophagitis. The symptoms prompting the endoscopic diagnoses included: gastrointestinal bleeding (OR 7.61; 95%CI 2.76-21.0), heartburn (OR 4.58; 95%CI 1.86-11.28), and cough (OR 3.59; 95%CI 1.34-9.62). Steroids (OR 2.68; 95%CI 1.11-6.44) and calcium antagonists (OR 1.50; 95%CI 0.79-2.87) were associated with esophagitis as risk factors, whereas proton pump inhibitors (OR 0.46; 95%CI 0.25-0.87), nitrates (OR 0.14; 95%CI 0.02-0.78), and sucralfate in males (OR 0.09; 95%CI 0.01-0.92) were associated as protective factors. Patients with esophagitis were discharged with an endocrinologic/metabolic-type diagnosis. Deaths were signifi- cantly higher among patients with esophagitis (25 vs. 9); more severe esophagitis was characterized by a higher Charlson comorbidity index and a greater presence of anorexia and nausea. Conclusions: These findings seem to substantiate the theory that esophagitis is a characteristic which exacerbates frailty in hospitalized elderly people and its identification may be helpful in these patients. (literal)
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