Expression of cytosolic branched chain aminotransferase (BCATc) mRNA in the developing mouse brain. (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Expression of cytosolic branched chain aminotransferase (BCATc) mRNA in the developing mouse brain. (Articolo in rivista) (literal)

Anno

• 2007-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.modgep.2006.10.010 (literal)

Alternative label

• Castellano S, Casarosa S, Sweatt AJ, Hutson SM, Bozzi Y. (2007)
  Expression of cytosolic branched chain aminotransferase (BCATc) mRNA in the developing mouse brain.
  in Gene expression patterns (Tokyo)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Castellano S, Casarosa S, Sweatt AJ, Hutson SM, Bozzi Y. (literal)

Pagina inizio

• 485 (literal)

Pagina fine

• 490 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 7 (literal)

Rivista

• Gene expression patterns (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• INCNR PISA (literal)

Titolo

• Expression of cytosolic branched chain aminotransferase (BCATc) mRNA in the developing mouse brain. (literal)

Abstract

• Branched-chain aminotransferase (BCAT) catalyzes the transamination of essential branched-chain amino acids (BCAAs: leucine, isoleucitic and valine) with alpha-ketoglutarate. Through this reaction, BCAAs provide nitrogen for the synthesis of glutamate, the predominant excitatory neurotransmitter. Two BCAT isoforms have been identified: one cytosolic (BCATc) and one mitochondrial (BCATm). In adult rodents, BCATc is expressed in a wide variety of structures of the central nervous system (CNS), in neurons. So far, no data were available about the expression of BCATc in the developing CNS. Here, we analyse the expression profile of BCATc mRNA in the mouse brain from embryonic day 12.5 to adult age. BCATc mRNA gradually appears in different brain regions starting from early stages of neural development, and is maintained until adulthood. BCATc mRNA is predominantly present in the cerebral cortex, hippocampus, thalamus, ventral midbrain, raphe, cerebellum and precerebellar system. This study represents the first detailed analysis of BCATc mRNA expression in the developing mouse brain. (literal)

Prodotto di

• Institute of neuroscience (IN) (Istituto)
• Plasticità e invecchiamento del sistema nervoso (ME.P02.006.001) (Modulo)

Autore CNR

• YURI BOZZI (Persona)

Incoming links:

Autore CNR di

• YURI BOZZI (Persona)

Prodotto

• Institute of neuroscience (IN) (Istituto)
• Plasticità e invecchiamento del sistema nervoso (ME.P02.006.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Gene expression patterns (Rivista)