The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax (Articolo in rivista) (literal)

Anno

• 2005-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.febslet.2005.05.055 (literal)

Alternative label

• Campello S; De Marchi U; Szabò I; Tombola F; Martinou JC; Zoratti M (2005)
  The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax
  in FEBS letters (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Campello S; De Marchi U; Szabò I; Tombola F; Martinou JC; Zoratti M (literal)

Pagina inizio

• 3695 (literal)

Pagina fine

• 3700 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/science/article/pii/S0014579305006769 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 579 (literal)

Rivista

• FEBS letters (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 17 (literal)

Note

• PubMe (literal)
• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Campello S; De Marchi U; Tombola F; Zoratti M: IN - Padova e Dip. Scienze Biomediche Sperimentali, Università di Padova. Szabò I: Dip. di Biologia, Università di Padova. Martinou JC: Dept. of Cell Biology, University of Geneva, Switzerland. (literal)

Titolo

• The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax (literal)

Abstract

• This paper explores the relationship between Bax and the mitochondrial permeability transition pore (PTP). Isolated human colon tumor (HCT116) Bax- mitochondria exposed to recombinant Bax exhibited a slow, cyclosporin A-sensitive swelling, but only at [Bax]>200 nM. The amount of Bax incorporated was much higher than that found in organelles isolated from HCT116 Bax+ staurosporine- or etoposide-treated apoptotic cells, casting doubts on the significance of the putative PT induction for apoptosis. Bax did not influence the electrophysiological properties of an approximately 1 nS channel ascribed to the Ca2+-dependent mitochondrial permeability transition pore. These observations indicate that the PTP is independent of Bax. (literal)

Prodotto di

• Istituto di neuroscienze (IN) (Istituto)
• Neurobiologia e Neuropatologia (ME.P02.005.001) (Modulo)

Autore CNR

• MARIO ZORATTI (Persona)

Insieme di parole chiave

• Parole chiave di "The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARIO ZORATTI (Persona)

Prodotto

• Istituto di neuroscienze (IN) (Istituto)
• Neurobiologia e Neuropatologia (ME.P02.005.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• FEBS letters (Rivista)

Insieme di parole chiave di

• Parole chiave di "The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax" (Insieme di parole chiave)