http://www.cnr.it/ontology/cnr/individuo/prodotto/ID37568
Lifestyle-related risk factors for Parkinson?s disease: a population-based study. (Articolo in rivista)
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- Label
- Lifestyle-related risk factors for Parkinson?s disease: a population-based study. (Articolo in rivista) (literal)
- Anno
- 2003-01-01T00:00:00+01:00 (literal)
- Alternative label
Baldereschi M, Di Carlo A, Vanni P, Ghetti A, Carbonin P, Amaducci L, Inzitari D (2003)
Lifestyle-related risk factors for Parkinson?s disease: a population-based study.
in Acta neurologica Scandinavica
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- Baldereschi M, Di Carlo A, Vanni P, Ghetti A, Carbonin P, Amaducci L, Inzitari D (literal)
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- ISI Web of Science (WOS) (literal)
- Titolo
- Lifestyle-related risk factors for Parkinson?s disease: a population-based study. (literal)
- Abstract
- OBJECTIVES: To investigate the association of major lifestyle-related risk factors with the prevalent cases of Parkinson's disease (PD) identified by the Italian Longitudinal Study on Aging. METHODS: A total of 5632 individuals randomly selected from the population registers of eight centers were screened for parkinsonism using both a questionnaire and a neurologic examination. Screened positives underwent a structured clinical work-up for the diagnosis of parkinsonism and parkinsonism subtypes. RESULTS: We identified 113 prevalent cases of PD. Age, male gender, and pesticide-use license were significantly related to PD. Heavy smoking was inversely related to PD. Age (OR = 1.1; 95% CI, 1.06-1.15) and pesticide-use license (OR = 3.7; 95% CI, 1.6-8.6) kept their significant correlation with the disease in the multivariate analysis to adjust for all the variables under investigation. Multivariate analyses were made for men and women separately: pesticide exposure was positively associated with PD only in men. CONCLUSIONS: Pesticide exposure might represent a candidate for environmental factors involved in PD. (literal)
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