Retinal organization in the bcl-2-overexpressing transgenic mouse. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Retinal organization in the bcl-2-overexpressing transgenic mouse. (Articolo in rivista) (literal)

Anno

• 2002-01-01T00:00:00+01:00 (literal)

Alternative label

• Strettoi E., Volpini M. (2002)
  Retinal organization in the bcl-2-overexpressing transgenic mouse.
  in Journal of comparative neurology (1911)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Strettoi E., Volpini M. (literal)

Pagina inizio

• 1 (literal)

Pagina fine

• 10 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 446 (literal)

Rivista

• Journal of comparative neurology (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Titolo

• Retinal organization in the bcl-2-overexpressing transgenic mouse. (literal)

Abstract

• Naturally occurring cell death is believed to play a major role during the development of the nervous system in the establishment of neuronal architecture. Here we study the effects of cell death inhibition by using a transgenic mouse in which the powerful antiapoptotic gene bcl-2 is expressed in neurons. The retina of this mouse reveals that the general neuronal plan has been maintained. However, bcl-2 overexpression leads to altered frequencies of the major cell types in the retina. Thus, it is possible to estimate cell-type-specific rates of apoptosis by observing the increases in numbers of cells in the bcl-2-overexpressing transgenic mouse. (literal)

Prodotto di

• Institute of neuroscience (IN) (Istituto)

Incoming links:

Prodotto

• Institute of neuroscience (IN) (Istituto)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of comparative neurology (Rivista)