http://www.cnr.it/ontology/cnr/individuo/prodotto/ID36489
Marine diatoms as optical biosensors (Articolo in rivista)
- Type
- Label
- Marine diatoms as optical biosensors (Articolo in rivista) (literal)
- Anno
- 2009-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1016/j.bios.2008.08.016 (literal)
- Alternative label
De Stefano L, Rotiroti L, De Stefano M, Lamberti A, Lettieri S, Setaro A, Maddalena P (2009)
Marine diatoms as optical biosensors
in Biosensors & bioelectronics
(literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- De Stefano L, Rotiroti L, De Stefano M, Lamberti A, Lettieri S, Setaro A, Maddalena P (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- 1. Inst Microelect & Microsyst, Unit Naples, I-80131 Naples, Italy
2. Univ Naples 2, Dept Environm Sci, I-81100 Caserta, Italy
3. Univ Naples Federico 2, Dept Biochem & Med Biotechnol, I-80100 Naples, Italy
4. Univ Naples Federico 2, Dept Phys Sci, I-80126 Naples, Italy
5. Univ Naples Federico 2, CNR INFM Coherentia, I-80126 Naples, Italy (literal)
- Titolo
- Marine diatoms as optical biosensors (literal)
- Abstract
- We have chemically modified the frustules of the marine diatom Coscinodiscus concinnus Wm. Smith to properly bind a highly selective bioprobe such as an antibody By measuring the changes in the photoluminescence emission of diatoms frustules, we have monitored the molecular recognition event between the antibody and its ligand: the dissociation constant estimated is of the same order of that measured by standard Biacore (R). The nanostructured silica frustules, a low-cost and natural available material, have shown high sensitivity, equal to 1.2 +/- 0.2 nm mu M-1, and a detection limit of 100 nM, and thus are quite ideal candidates for lab-on-particle applications. (literal)
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- Autore CNR
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