http://www.cnr.it/ontology/cnr/individuo/prodotto/ID33066
Diastereoselective Synthesis of the Indenylruthenium(II) Complexes [Ru(n5-C9H7){k3(P,C,C)-Ph2P(CH2CR=CH2))(PPh3)][PF6](R = H, Me): Enantiofacial Coordination, Hemilabile Properties, and Diastereoselective Nucelophilic Additions to k3 (P,C,C)-Allylphosphin (Articolo in rivista)
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- Diastereoselective Synthesis of the Indenylruthenium(II) Complexes [Ru(n5-C9H7){k3(P,C,C)-Ph2P(CH2CR=CH2))(PPh3)][PF6](R = H, Me): Enantiofacial Coordination, Hemilabile Properties, and Diastereoselective Nucelophilic Additions to k3 (P,C,C)-Allylphosphin (Articolo in rivista) (literal)
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- 2004-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1021/om040001q (literal)
- Alternative label
Alvarez P., Lastra E., Gimeno J., BrañaP., Sordo J. A., Gomez J., Favello L. R., Bassetti M. (2004)
Diastereoselective Synthesis of the Indenylruthenium(II) Complexes [Ru(n5-C9H7){k3(P,C,C)-Ph2P(CH2CR=CH2))(PPh3)][PF6](R = H, Me): Enantiofacial Coordination, Hemilabile Properties, and Diastereoselective Nucelophilic Additions to k3 (P,C,C)-Allylphosphin
in Organometallics; ACS, American chemical society, Washington, DC (Stati Uniti d'America)
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- Alvarez P., Lastra E., Gimeno J., BrañaP., Sordo J. A., Gomez J., Favello L. R., Bassetti M. (literal)
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- Departamento de Quimica Organica e Inorganica, Instituto de Quimica Organometalica
\"Enrique Moles\" (Unidad Asociada al CSIC), and Laboratorio de Quimica Computacional,
Departamento de Quimica Fisica y Analitica, Universidad de Oviedo, Oviedo, Principado de
Asturias, Spain, Department of Chemistry, Universidad de La Rioja, Complejo Cientifico
Tecnologico, Calle Madre de Dios, 51, 26006 Logron~o, Spain, Departamento de Quimica
Inorganica, Facultad de Ciencias, Universidad de Zaragoza-CSIC, E-50009 Zaragoza, Spain,
and Istituto CNR di Metodologie Chimiche, Sezione Meccanismi di Reazione, and
Dipartimento di Chimica, Universita` \"La Sapienza\", 00185 Roma, Italy (literal)
- Titolo
- Diastereoselective Synthesis of the Indenylruthenium(II) Complexes [Ru(n5-C9H7){k3(P,C,C)-Ph2P(CH2CR=CH2))(PPh3)][PF6](R = H, Me): Enantiofacial Coordination, Hemilabile Properties, and Diastereoselective Nucelophilic Additions to k3 (P,C,C)-Allylphosphin (literal)
- Abstract
- The mixed-phosphine complexes [Ru(è5-C9H7)Cl{k1(P)-Ph2P(CH2CRdCH2)}(PPh3)] (R )
H (1a), Me (1b)) are prepared by phosphine exchange reactions (1:1 molar ratio) of [Ru(eta-5-
C9H7)Cl(PPh3)2] with the corresponding allylphosphines Ph2P(CH2CRdCH2) in refluxing THF.
The reaction of 1a with sodium methoxide in methanol yields the hydride derivative [Ru-
(eta-5-C9H7)H{k1(P)-Ph2P(CH2CHdCH2)}(PPh3)] (1c). The treatment of complexes 1a and 1b
with NaPF6 in methanol diastereoselectively affords the cationic complexes [Ru(eta-5-C9H7)-
{k3(P,C,C)-Ph2P(CH2CRdCH2)}(PPh3)][PF6] (R ) H (2a), Me (2b)) in good yield. An X-ray
crystal structure determination of complex 2a shows that the si enantiofacial coordination
of the olefin group accompanies the R relative configuration of the metal center. No
epimerization process has been observed. Olefin exchange substitution reactions of complex
2a with MeCN and BzCN (1:1.5 molar ratio) in refluxing CH2Cl2 yield the cationic complexes
[Ru(eta-5-C9H7)(NCR){k1(P)-Ph2P(CH2CHdCH2)}(PPh3)][PF6] (R) Me (3a), Bz (3b)). Similarly,
the neutral complexes [Ru(è5-C9H7)(N3){k1(P)-Ph2P(CH2CRdCH2)}(PPh3)] (R ) H (4a), Me
(4b)) are obtained by the treatment of complexes 2a,b with sodium azide in THF/MeOH at
room temperature. The addition of lithium carbanions LiR¢ (R¢ ) Me, nBu) to solutions of
complexes 2a,b in tetrahydrofuran results in regio- and stereoselective exo addition at the
Câ atom of the coordinated allylic group, affording the ruthenacyclopentane complexes [Ru-
(eta-5-C9H7){k2(P,C)-Ph2P{CH2C(R)(R¢)CH2}}(PPh3)] (R ) H) Me (5a), nBu (5b); R ) Me,
R¢ ) Me (6a), nBu (6b)) in 80-95% yield. Similarly, the complexes [Ru(eta-5-C9H7){k2(P,C)-
Ph2P{CH2CH(R)CH2}}(PPh3)] (R ) H (5c), Me (6c)) are formed by the reaction of equimolar
mixtures of complexes 2a,b with Li[B(C2H5)3H]. The molecular structure and relative
configurations RRuS/SRuR of the new stereogenic atoms of complex 5b have been determined
by X-ray diffraction. Kinetic studies on the substitution reaction of complex 2a with CD3CN
in CDCl3 indicate that the olefin exchange occurs via parallel first-order (dissociative) and
second-order (associative) pathways and highlight the intermediacy of a transient coordinatively
unsaturated species, formed by olefin dissociation before attack of the nitrile. (literal)
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