Stereochemical aspects of the asymmetric synthesis of chiral alpha,beta-dihydroxy phosphonates. Synthesis of alpha,beta-dihydroxy phosphonic acids (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Stereochemical aspects of the asymmetric synthesis of chiral alpha,beta-dihydroxy phosphonates. Synthesis of alpha,beta-dihydroxy phosphonic acids (Articolo in rivista) (literal)

Anno

• 1996-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/S0957-4166(96)00456-9 (literal)

Alternative label

• Bongini A.; Camerini R.; Panunzio M.; Bandini E.; Martelli G.; Spunta G. (1996)
  Stereochemical aspects of the asymmetric synthesis of chiral alpha,beta-dihydroxy phosphonates. Synthesis of alpha,beta-dihydroxy phosphonic acids
  in Tetrahedron: asymmetry (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Bongini A.; Camerini R.; Panunzio M.; Bandini E.; Martelli G.; Spunta G. (literal)

Pagina inizio

• 3485 (literal)

Pagina fine

• 3504 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.sciencedirect.com/science/article/pii/S0957416696004569 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 7 (literal)

Rivista

• Tetrahedron: asymmetry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 12 (literal)

Note

• Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Dipto. di Chim. G. Ciamician U., C.S.F.M.-C.N.R., Via Selmi, 2, 40126 Bologna; I.Co.C.E.A.-C.N.R., Via Gobetti, 101-40129 Bologna (literal)

Titolo

• Stereochemical aspects of the asymmetric synthesis of chiral alpha,beta-dihydroxy phosphonates. Synthesis of alpha,beta-dihydroxy phosphonic acids (literal)

Abstract

• Stereocontrol in the asymmetric phosphonylation of aldehydes via organophosphorous esters has been obtained starting from chiral aldehydes. The nature of the O-protecting group is crucial to obtain, in terms of diastereoselectivity and chemical yields, the best results. An ab initio molecular orbital study on 2-silyloxy propanal and MM2 studies on 2-alkoxy propanal show the existence of stable cyclic and acyclic conformers, which are presumably responsible for the high syn diastereoselectivity observed in the addition of non-metal carrying phosphites. (literal)

Prodotto di

• Sintesi e caratterizzazione mediante metodologie chimiche innovative, di scaffold molecolari per l'individuazione di nuove molecole biologicamente attive. (PM.P03.011.002) (Modulo)
• Institute for organic syntheses and photoreactivity (ISOF) (Istituto)

Autore CNR

• ELISA BANDINI (Persona)

Incoming links:

Prodotto

• Institute for organic syntheses and photoreactivity (ISOF) (Istituto)
• Sintesi e caratterizzazione mediante metodologie chimiche innovative, di scaffold molecolari per l'individuazione di nuove molecole biologicamente attive. (PM.P03.011.002) (Modulo)

Autore CNR di

• ELISA BANDINI (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Tetrahedron: asymmetry (Rivista)