http://www.cnr.it/ontology/cnr/individuo/prodotto/ID323583

Cerebellar metabolic involvement and its correlations with clinical parameters in vestibular neuritis (Articolo in rivista)

Type

Prodotto della ricerca (Classe)
Articolo in rivista (Classe)

Label

Cerebellar metabolic involvement and its correlations with clinical parameters in vestibular neuritis (Articolo in rivista) (literal)

Anno

2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1007/s00415-014-7449-x (literal)

Alternative label

Alessandrini, Marco; Micarelli, Alessandro; Bruno, Ernesto; Chiaravalloti, Agostino; Pietro, Barbara Di; Schillaci, Orazio; Candidi, Matteo; Öberg, Johanna; Pagani, Marco (2014)
Cerebellar metabolic involvement and its correlations with clinical parameters in vestibular neuritis
in Journal of neurology (Print); Springer-Medizin-Verl., Heidelberg (Germania)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Alessandrini, Marco; Micarelli, Alessandro; Bruno, Ernesto; Chiaravalloti, Agostino; Pietro, Barbara Di; Schillaci, Orazio; Candidi, Matteo; Öberg, Johanna; Pagani, Marco (literal)

Pagina inizio

1976 (literal)

Pagina fine

1985 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

http://www.scopus.com/record/display.url?eid=2-s2.0-84914708214&origin=inward (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

261 (literal)

Rivista

Journal of neurology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

1 (literal)

Note

Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

Universita degli Studi di Roma Tor Vergata; IRCCS Fondazione Santa Lucia; Karolinska University Hospital; Istituto Neurologico Mediterraneo Neuromed, Pozzilli; Istituto Di Scienze E Tecnologie Della Cognizione, Rome (literal)

Titolo

Cerebellar metabolic involvement and its correlations with clinical parameters in vestibular neuritis (literal)

Abstract

Although vestibular neuritis (VN) cortical models are described in the literature, there is lack of knowledge regarding the exclusive cerebellar involvement. The aim of the present study was to analyze, by [18F] fluorodeoxyglucose-positron emission tomography (FDGPET)/ computer tomography, regional cerebellar FDG uptake in eight right-handed VN patients (five females; three males; mean age 48 ± 7 years) during the first few days (PET0) and after 1 month (PET1) since symptoms onset. At both phases, patients underwent otoneurological examination and filled in a battery of validated questionnaires. Twenty-six cerebellar volumes of interest (VOI) were identified by the automated anatomical labeling library and normalized to thalamus FDG-PET uptake. Mean intensity within VOIs was calculated in both phases and processed by within-subjects ANOVA. A significantly lower (p<0.005) FDG uptake distribution was found in bilateral lobules III, VI and X and in vermis 1-2, 3, 6 and 10 at PET0 as compared to PET1 and a significant higher FDG uptake distribution was found in right crus I in the same comparison. Significant (p<0.05) positive correlations were found between Anxiety and Bucket test scores, and normalized metabolism in right crus I (at PET0) and vermis 10 (at PET1), respectively. A negative correlation was found at PET0 between slow-phase velocity scores and normalized metabolism in right lobule X. These data show relevant changes in the pattern of cerebellar metabolism that might unravel additional central aspects of early and late VN associated to bilateral cortical responses to sensory conflict during the acute VN-related controversial inflow. (literal)

Editore