http://www.cnr.it/ontology/cnr/individuo/prodotto/ID323020

Oesophageal atresia: prevalence, prenatal diagnosis and associated anomalies in 23 European regions (Articolo in rivista)

Type

Prodotto della ricerca (Classe)
Articolo in rivista (Classe)

Label

Oesophageal atresia: prevalence, prenatal diagnosis and associated anomalies in 23 European regions (Articolo in rivista) (literal)

Anno

2012-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1136/archdischild-2011-300597 (literal)

Alternative label

1 Pedersen, Rikke Neess; 2Calzolari, Elisa; 3 Husby, Steffen; 4 Garne, Ester; 5 Bianchi, Fabrizio; EUROCAT working group (2012)
Oesophageal atresia: prevalence, prenatal diagnosis and associated anomalies in 23 European regions
in Archives of disease in childhood; BMJ Publishing Group (British Medical Journals), London (Regno Unito)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

1 Pedersen, Rikke Neess; 2Calzolari, Elisa; 3 Husby, Steffen; 4 Garne, Ester; 5 Bianchi, Fabrizio; EUROCAT working group (literal)

Pagina inizio

227 (literal)

Pagina fine

232 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

97 (literal)

Rivista

Archives of disease in childhood (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

6 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

3 (literal)

Note

PubMe (literal)
ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

1Department of Pediatrics, Odense University Hospital, Odense, Denmark 2Genetic Section, Department of Experimental Medicine and Diagnosis, University of Ferrara, Ferrara, Italy 3Department of Pediatrics, Hans Christian Andersen Children's Hospital, Odense, Denmark 4Department of Paediatrics, Lillebaelt Hospital, Kolding, Denmark, 5 Unit of Epidemiology, IFC CNR, (literal)

Titolo

Oesophageal atresia: prevalence, prenatal diagnosis and associated anomalies in 23 European regions (literal)

Abstract

Objective To describe prevalence, prenatal diagnosis and epidemiological data on oesophageal atresia from 23 well-defi ned European regions and compare the prevalence between these regions. Design Population-based study using data from a large European database for surveillance of congenital anomalies (EUROCAT) for two decades (1987-2006). Settings Twenty-three participating registries based on multiple sources of information including information about live births, fetal deaths with gestational age >=20 weeks and terminations of pregnancy. Patients 1222 cases of oesophageal atresia in apopulation of 5 019 804 births. Results The overall prevalence was 2.43 cases per 10 000 births (95% CI 2.30 to 2.57). There were regional differences in prevalence ranging from 1.27 to 4.55. Prenatal detection rates varied by registry from >50% of cases to <10% of cases. A total of 546 cases (44.7%) had an isolated oesophageal anomaly, 386 (31.6%) were multiple malformed and 290 (23.7%) had an association or a syndrome. There were 1084 live born cases (88.7%), 43 cases were fetal deaths and 95 cases were terminations of pregnancy. One-week survival for live births was 86.9% and 99.2% if the gestational age was >=38 weeks and isolated oesophageal atresia was present. Males accounted for 57.3% of all cases and 38.5% of live born cases were born with gestational age <37 weeks. Conclusion There were regional differences in prevalence of oesophageal atresia in Europe. Half of all cases had associated anomalies. Prenatal detection rate increased from 26% to 36.5% over the two decades. Survival in infants with isolated oesophageal atresia born at term is high. (literal)

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