http://www.cnr.it/ontology/cnr/individuo/prodotto/ID322141

Assessing appendicular skeletal muscle mass with bioelectrical impedance analysis in free-living Caucasian older adults (Articolo in rivista)

Type

Articolo in rivista (Classe)
Prodotto della ricerca (Classe)

Label

Assessing appendicular skeletal muscle mass with bioelectrical impedance analysis in free-living Caucasian older adults (Articolo in rivista) (literal)

Anno

2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

10.1016/j.clnu.2014.07.010 (literal)

Alternative label

Sergi, Giuseppe; De Rui, Marina; Veronese, Nicola; Bolzetta, Francesco; Berton, Linda; Carraro, Sara; Bano, Giulia; Coin, Alessandra; Manzato, Enzo; Perissinotto, Egle (2014)
Assessing appendicular skeletal muscle mass with bioelectrical impedance analysis in free-living Caucasian older adults
in Clinical nutrition (Edinb.)
(literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

Sergi, Giuseppe; De Rui, Marina; Veronese, Nicola; Bolzetta, Francesco; Berton, Linda; Carraro, Sara; Bano, Giulia; Coin, Alessandra; Manzato, Enzo; Perissinotto, Egle (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

http://www.ncbi.nlm.nih.gov/pubmed/25103151 (literal)

Rivista

Clinical nutrition (Rivista)

Note

Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

1 -8: Department of Medicine e DIMED, Geriatrics Division, University of Padova, Padova, Italy; 9: Department of Medicine e DIMED, Geriatrics Division, University of Padova, Padova, Italy b National Research Council, Aging Branch, Institute of Neuroscience, Padova, Italy; 10: Department of Cardiac, Thoracic and Vascular Sciences, Biostatistics, Epidemiology and Public Health Unit, University of Padova, Padova, Italy (literal)

Titolo

Assessing appendicular skeletal muscle mass with bioelectrical impedance analysis in free-living Caucasian older adults (literal)

Abstract

Background & aims: Aging is characterized by a loss of appendicular skeletal muscle mass (ASMM) leading to physical disability and death. Bioelectrical impedance analysis (BIA) is reliable in estimating ASMM but no prediction equations are available for elderly Caucasian subjects. The aim of the study was to develop and validate an equation derived from bioelectrical impedance analysis (BIA) to predict appendicular skeletal muscle mass (ASMM) in healthy Caucasian elderly subjects, taking dual X-ray absorptiometry (DXA) as the reference method, and comparing the reliability of the new equation with another BIA-based model developed by Kyle et al. (Kyle UG, Genton L, Hans D, Pichard C, 2003). Methods: With a cross-sectional design, 296 free-living, healthy Caucasian subjects (117 men, 179 women) over 60 years of age were enrolled. Lean mass of limbs was measured with DXA to ascertain ASMM (ASMMDxA). Whole-body tetrapolar BIA was performed to measure resistance (Rz), resistance normalized for stature (RI), and reactance (Xc). The BIA multiple regression equation for predicting ASMM was developed using a double cross-validation technique. The predicted ASMM values were compared with ASMMKyle, i.e. ASMM estimates derived from the model developed by Kyle et al. (Kyle et al., 2003). Results: Cross-validation resulted in a unique equation using the whole sample: ASMM (kg) ¼ 3.964 þ (0.227*RI) þ (0.095*weight) þ (1.384*sex) þ (0.064*Xc) [R2 ¼ 0.92 and SEE ¼ 1.14 kg]. In our sample, ASMMKyle differed significantly from the ASMMDxA (p < 0.0001), with a mean error of 0.97 ± 1.34 kg (5.1 ± 6.9%). Unlike the present BIA prediction equation, the Kyle et al. model showed a correlation between the bias and the mean of ASMMDxA and ASMMKyle (r ¼ 0.406, p < 0.001). Conclusion: The new BIA equation provides a valid estimate of ASMM in older Caucasian adults. (literal)

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