hMSC interaction with pcl and pcl/gelatin platforms: a comparative study on films and electrospun membranes (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• hMSC interaction with pcl and pcl/gelatin platforms: a comparative study on films and electrospun membranes (Articolo in rivista) (literal)

Anno

• 2011-01-01T00:00:00+01:00 (literal)

Alternative label

• Guarino V.; Alvarez-Perez MA; Cirillo V; Ambrosio L; (2011)
  hMSC interaction with pcl and pcl/gelatin platforms: a comparative study on films and electrospun membranes
  in Journal of bioactive and compatible polymers (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Guarino V.; Alvarez-Perez MA; Cirillo V; Ambrosio L; (literal)

Pagina inizio

• 144 (literal)

Pagina fine

• 160 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 26 (literal)

Rivista

• Journal of bioactive and compatible polymers (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note

• DOI: 10.1177/0883911511399410 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• IMCB/CNR (literal)

Titolo

• hMSC interaction with pcl and pcl/gelatin platforms: a comparative study on films and electrospun membranes (literal)

Abstract

• Polycaprolactone (PCL) and PCL/gelatin membranes and films were fabricated by electrospinning and solvent casting. A systematic analysis of the morphology evolution as degradation occurs was made to separate the contribution of fiber nanotexture and gelatin biochemical signal on cell adhesion and proliferation. Field emission scanning electron microscope was used to assess the contribution of platform architecture on the gelatin degradation by the morphological changes that occurred at different times. The evaluation of human mesenchymal stem cells’biocompatibility confirmed the role of architecture and chemical composition on cell response. The nanostructured surfaces positively affected the cell recognition by increasing the surface area. The gelatin embedded in the PCL matrix of the nanofibers improved the cell/material interaction and provided support to the proliferation. The PCL/gelatin electrospun membranes showed an increase in mineralization when conditioned in osteogenic medium; this system has promise for long-term in vitro investigations of bone regeneration (literal)

Prodotto di

• Biomateriali ed ingegneria dei tessuti (PM.P02.004.002) (Modulo)
• Institute for composite and biomedical materials (IMCB) (Istituto)

Autore CNR

• Valentina Cirillo (Persona)
• Marco Antonio Alvarez Pérez (Unità di personale esterno)
• LUIGI AMBROSIO (Unità di personale interno)
• VINCENZO GUARINO (Persona)

Insieme di parole chiave

• Keywords of "hMSC interaction with pcl and pcl/gelatin platforms: a comparative study on films and electrospun membranes" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute for composite and biomedical materials (IMCB) (Istituto)
• Biomateriali ed ingegneria dei tessuti (PM.P02.004.002) (Modulo)

Autore CNR di

• VINCENZO GUARINO (Persona)
• LUIGI AMBROSIO (Unità di personale interno)
• Marco Antonio Alvarez Pérez (Unità di personale esterno)
• Valentina Cirillo (Persona)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Journal of bioactive and compatible polymers (Rivista)

Insieme di parole chiave di

• Keywords of "hMSC interaction with pcl and pcl/gelatin platforms: a comparative study on films and electrospun membranes" (Insieme di parole chiave)