http://www.cnr.it/ontology/cnr/individuo/prodotto/ID31870
Dynamic-mechanical properties of a novel composite intervertebral disc prosthesis (Articolo in rivista)
- Type
- Label
- Dynamic-mechanical properties of a novel composite intervertebral disc prosthesis (Articolo in rivista) (literal)
- Anno
- 2007-01-01T00:00:00+01:00 (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Gloria A.*; Causa F.***; De Santis R.*; Netti P.A.**; Ambrosio L.* (literal)
- Pagina inizio
- Pagina fine
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- Note
- ISI Web of Science (WOS) (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- *Institute of Composite and Biomedical Materials, P.le Tecchio
80, 80125 Naples, Italy
**P.A. Netti,Interdisciplinary Research Centre in Biomaterials, University of Naples Federico II, P.le Tecchio.80, 80125 Naples, Italy
***F. Causa, Department of Experimental and Clinical Medicine, University
of Magna Graecia, Germaneto 88100 Catanzaro, Italy (literal)
- Titolo
- Dynamic-mechanical properties of a novel composite intervertebral disc prosthesis (literal)
- Abstract
- Over the past years, a tremendous effort has
been made to develop an intervertebral disc (IVD) prosthesis
with suitable biological, mechanical and transport
properties. However, it has been frequently reported that
current prostheses undergo failure mainly due to the mismatch
between the mechanical properties of the conventional
device and the spine segment to be replaced. The aim
of the present work was to develop a poly(2-hydroxyethyl
methacrylate)/poly(methyl methacrylate) (PHEMA/
PMMA) (80/20 w/w) semi-interpenetrating polymer network
(s-IPN) composite hydrogel reinforced with
poly(ethylene terephthalate) (PET) fibres, and to investigate
the static and dynamic mechanical properties. Filament
winding and moulding technologies were employed
to obtain the composite IVD prostheses with the unique
complex structure that is peculiar to the natural IVD. The
compressive properties analysis showed the typical
J-shaped stress-strain curve which is displayed by natural
IVDs. Compressive modulus varied from 84 to 120 MPa,
as a function of the strain rate, and stress was higher than
10 MPa. These values are in the range of those of the
natural lumbar IVDs. No failure of the prostheses has
occurred during fatigue test performed for ten million
cycles in physiological solution. Dynamic mechanical tests
have confirmed the composite IVD prostheses exhibited
appropriate viscoelastic properties. (literal)
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