Axial iron coordination and spin state change in a heme c upon electrostatic protein-SAM interaction (Articolo in rivista)

Type
Label
  • Axial iron coordination and spin state change in a heme c upon electrostatic protein-SAM interaction (Articolo in rivista) (literal)
Anno
  • 2013-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1039/c3cp50222h (literal)
Alternative label
  • Di Rocco G.; Ranieri A.; Bortolotti C.A.; Battistuzzi G.; Bonifacio A.; Sergo V.; Borsari M.; Sola M. (2013)
    Axial iron coordination and spin state change in a heme c upon electrostatic protein-SAM interaction
    in PCCP. Physical chemistry chemical physics (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Di Rocco G.; Ranieri A.; Bortolotti C.A.; Battistuzzi G.; Bonifacio A.; Sergo V.; Borsari M.; Sola M. (literal)
Pagina inizio
  • 13499 (literal)
Pagina fine
  • 13505 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url
  • http://www.scopus.com/inward/record.url?eid=2-s2.0-84884179531&partnerID=q2rCbXpz (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 15 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 32 (literal)
Note
  • Scopu (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 183, I-41125 Modena, Italy; CNR-NANO Institute of Nanoscience, Via Campi 213/A, I-41125 Modena, Italy; Department of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Via Campi 183, 41125 Modena, Italy; Department of Materials and Natural Resources, University of Trieste, Via Valerio 2, 34127 Trieste, Italy (literal)
Titolo
  • Axial iron coordination and spin state change in a heme c upon electrostatic protein-SAM interaction (literal)
Abstract
  • A bacterial di-heme cytochrome c binds electrostatically to a gold electrode surface coated with a negatively charged COOH-terminated SAM adopting a sort of 'perpendicular' orientation. Cyclic voltammetry, Resonance Raman and SERRS spectroscopies indicate that the high-potential C-terminal heme center proximal to the SAM's surface undergoes an adsorption-induced swapping of one axial His ligand with a water molecule, which is probably lost in the reduced form, and a low- to high-spin transition. This coordination change for a bis-His ligated heme center upon an electrostatically-driven molecular recognition is as yet unprecedented, as well as the resulting increase in reduction potential. We discuss it in comparison with the known methionine ligand lability in monoheme cytochromes c occurring upon interaction with charged molecular patches. One possible implication of this finding in biological ET is that mobile redox partners do not behave as rigid and invariant bodies, but in the ET complex are subjected to molecular changes and structural fluctuations that affect in a complex way the thermodynamics and the kinetics of the process. © 2013 The Owner Societies. (literal)
Prodotto di
Autore CNR

Incoming links:


Autore CNR di
Prodotto
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
data.CNR.it