Indobufen versus warfarin in the secondary prevention of major vascular events in nonrheumatic atrial fibrillation (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Indobufen versus warfarin in the secondary prevention of major vascular events in nonrheumatic atrial fibrillation (Articolo in rivista) (literal)

Anno

• 1997-01-01T00:00:00+01:00 (literal)

Alternative label

• Morocutti, C; Amabile, G; Fattapposta, F; Nicolosi, A; Matteoli, S; Trappolini, M; Cataldo, G; Milanesi, G; Lavezzari, M; Pamparana, F; Coccheri, S (1997)
  Indobufen versus warfarin in the secondary prevention of major vascular events in nonrheumatic atrial fibrillation
  in Stroke
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Morocutti, C; Amabile, G; Fattapposta, F; Nicolosi, A; Matteoli, S; Trappolini, M; Cataldo, G; Milanesi, G; Lavezzari, M; Pamparana, F; Coccheri, S (literal)

Pagina inizio

• 1015 (literal)

Pagina fine

• 1021 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 28 (literal)

Rivista

• Stroke (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 7 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 5 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Consiglio Nazionale delle Ricerche (CNR); POLICLIN UMBERTO I; OSPED CA GRANDA MILANO; OSPED CREMA; Pfizer; University of Bologna (literal)

Titolo

• Indobufen versus warfarin in the secondary prevention of major vascular events in nonrheumatic atrial fibrillation (literal)

Abstract

• Background and Purpose The results of a large prospective randomized trial have shown the efficacy of oral anticoagulation in the secondary prevention of major vascular events in patients with nonrheumatic atrial fibrillation (NRAF); less well established is the role of antiplatelet agents. The present study compared the effects of indobufen, a reversible inhibitor of platelet cyclooxygenase, with those of warfarin in this setting. Methods A total of 916 patients with NRAF and a recent (less than or equal to 15 days) cerebral ischemic episode were admitted to this multicenter, randomized study, during which they were treated with either indobufen (100 or 200 mg BID) or warfarin (to obtain an international normalized ratio of 2.0 to 3.5) for 12 months. The two groups (462 on indobufen and 454 on warfarin) were well balanced in terms of their main baseline characteristics. The primary outcome of the study was the combined incidence of nonfatal stroke (including intracerebral bleeding), pulmonary or systemic embolism, nonfatal myocardial infarction, and vascular death. (literal)

Prodotto di

• Gestione dei dati e conduzione di ricerche epidemiologiche applicate a diverse malattie. (ME.P07.008.001) (Modulo)

Autore CNR

• ALFREDO NICOLOSI (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "Indobufen versus warfarin in the secondary prevention of major vascular events in nonrheumatic atrial fibrillation" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ALFREDO NICOLOSI (Unità di personale interno)

Prodotto

• Gestione dei dati e conduzione di ricerche epidemiologiche applicate a diverse malattie. (ME.P07.008.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Stroke (Rivista)

Insieme di parole chiave di

• Parole chiave di "Indobufen versus warfarin in the secondary prevention of major vascular events in nonrheumatic atrial fibrillation" (Insieme di parole chiave)