Genomic analysis: Toward a new approach in breast cancer management (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Genomic analysis: Toward a new approach in breast cancer management (Articolo in rivista) (literal)

Anno

• 2012-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.critrevonc.2011.03.006 (literal)

Alternative label

• Cavallaro, Sebastiano; Paratore, Sabrina; de Snoo, Femke; Salomone, Edvige; Villari, Loredana; Buscarino, Calogero; Ferrau, Francesco; Banna, Giuseppe; Furci, Marco; Strazzanti, Angela; Cunsolo, Rosario; Pezzino, Salvatore; Gangi, Santi; Basile, Francesco (2012)
  Genomic analysis: Toward a new approach in breast cancer management
  in Critical reviews in oncology/hematology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Cavallaro, Sebastiano; Paratore, Sabrina; de Snoo, Femke; Salomone, Edvige; Villari, Loredana; Buscarino, Calogero; Ferrau, Francesco; Banna, Giuseppe; Furci, Marco; Strazzanti, Angela; Cunsolo, Rosario; Pezzino, Salvatore; Gangi, Santi; Basile, Francesco (literal)

Pagina inizio

• 207 (literal)

Pagina fine

• 223 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 81 (literal)

Rivista

• Critical reviews in oncology/hematology (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 17 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Italian Natl Res Council; University of Catania; Agendia BV (literal)

Titolo

• Genomic analysis: Toward a new approach in breast cancer management (literal)

Abstract

• Breast cancer is a clinically heterogeneous and complex disease that can affect differently individuals with seemingly identical clinicopathologic parameters. This heterogeneity is strictly linked to individuals and tumors genetic variability. Currently, the development of high-throughput technologies are proving novel tools to tackle this complexity. By DNA microarray technology, genomic analysis has been used successfully for breast carcinomas stratification into molecular subgroups with relevant implications for clinical outcomes, and detection of prognostic/treatment predictive signatures. Indeed, DNA microarray has rapidly improved becoming a powerful diagnostic tool. Information derived from these assays allows clinicians to estimate the risk for distant recurrence, and predict accurately which patients are likely to benefit from adjuvant therapy. This review will describe the state-of-the-art of genomic analysis in breast cancer and introduce the clinicians to a genomic approach to cancer management, illustrating how it can help in defying a better diagnosis, prognosis and therapeutic treatment. (C) 2011 Elsevier Ireland Ltd. All rights reserved. (literal)

Prodotto di

• Genomica funzionale delle malattie ereditarie del sistema nervoso (ME.P05.010.001) (Modulo)
• Institute of neurological sciences (ISN) (Istituto)

Autore CNR

• SABRINA PARATORE (Unità di personale esterno)
• SEBASTIANO CAVALLARO (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Genomic analysis: Toward a new approach in breast cancer management" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• SEBASTIANO CAVALLARO (Unità di personale interno)
• SABRINA PARATORE (Unità di personale esterno)

Prodotto

• Institute of neurological sciences (ISN) (Istituto)
• Genomica funzionale delle malattie ereditarie del sistema nervoso (ME.P05.010.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Critical reviews in oncology/hematology (Rivista)

Insieme di parole chiave di

• Keywords of "Genomic analysis: Toward a new approach in breast cancer management" (Insieme di parole chiave)