In-Check system: A highly integrated silicon Lab-on-Chip for sample preparation, PCR amplification and microarray detection of nucleic acids directly from biological samples (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• In-Check system: A highly integrated silicon Lab-on-Chip for sample preparation, PCR amplification and microarray detection of nucleic acids directly from biological samples (Articolo in rivista) (literal)

Anno

• 2013-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.snb.2012.09.068 (literal)

Alternative label

• Petralia, Salvatore; Verardo, Roberto; Klaric, Enio; Cavallaro, Sebastiano; Alessi, Enrico; Schneider, Claudio (2013)
  In-Check system: A highly integrated silicon Lab-on-Chip for sample preparation, PCR amplification and microarray detection of nucleic acids directly from biological samples
  in Sensors and actuators. B, Chemical (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Petralia, Salvatore; Verardo, Roberto; Klaric, Enio; Cavallaro, Sebastiano; Alessi, Enrico; Schneider, Claudio (literal)

Pagina inizio

• 99 (literal)

Pagina fine

• 105 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 187 (literal)

Rivista

• Sensors and actuators. B, Chemical (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 7 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• STMicroelectronics; Lab Nazl CIB; Proxenia Srl; Italian Natl Res Council (literal)

Titolo

• In-Check system: A highly integrated silicon Lab-on-Chip for sample preparation, PCR amplification and microarray detection of nucleic acids directly from biological samples (literal)

Abstract

• The development of a simple and rapid point-of-care clinical diagnostic device is essential for the evolution of sensing in healthcare technologies. In this study we introduce a fully integrated method for the detection of nucleic acids from cultured human cells and whole blood using the In-Check system supplied by STMicroelectronics. (literal)
• This work represents the first step toward the integration of sample preparation, nucleic acids amplification and DNA microarray detection into a simple and fast silicon Lab-on-Chip system. In particular, we report the experimental results for the detection of the human beta-globine gene (HBB) directly from defined numbers of cultured human cells and whole blood in less than 2 h. The influence of PCR inhibitors was also evaluated when the detection was performed on whole blood. (literal)

Prodotto di

• Genomica funzionale delle malattie ereditarie del sistema nervoso (ME.P05.010.001) (Modulo)
• Institute of neurological sciences (ISN) (Istituto)

Autore CNR

• SEBASTIANO CAVALLARO (Unità di personale interno)

Insieme di parole chiave

• Keywords of "In-Check system: A highly integrated silicon Lab-on-Chip for sample preparation, PCR amplification and microarray detection of nucleic acids directly from biological samples" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• SEBASTIANO CAVALLARO (Unità di personale interno)

Prodotto

• Institute of neurological sciences (ISN) (Istituto)
• Genomica funzionale delle malattie ereditarie del sistema nervoso (ME.P05.010.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Sensors and actuators. B, Chemical (Rivista)

Insieme di parole chiave di

• Keywords of "In-Check system: A highly integrated silicon Lab-on-Chip for sample preparation, PCR amplification and microarray detection of nucleic acids directly from biological samples" (Insieme di parole chiave)