Antimutagenic and Antioxidant Activity of a Selected Lectin-free Common Bean (Phaseolus vulgaris L.) in Two Cell-based Models (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Antimutagenic and Antioxidant Activity of a Selected Lectin-free Common Bean (Phaseolus vulgaris L.) in Two Cell-based Models (Articolo in rivista) (literal)

Anno

• 2015-01-01T00:00:00+01:00 (literal)

Alternative label

• Frassinetti S1, Gabriele M, Caltavuturo L, Longo V, Pucci L. (2015)
  Antimutagenic and Antioxidant Activity of a Selected Lectin-free Common Bean (Phaseolus vulgaris L.) in Two Cell-based Models
  in Plant foods for human nutrition (Dordr., Online)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Frassinetti S1, Gabriele M, Caltavuturo L, Longo V, Pucci L. (literal)

Rivista

• Plant foods for human nutrition (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Istituti Biologia e Biotecnologia Agraria, CNR (literal)

Titolo

• Antimutagenic and Antioxidant Activity of a Selected Lectin-free Common Bean (Phaseolus vulgaris L.) in Two Cell-based Models (literal)

Abstract

• Legumes and particularly beans are a key food of Mediterranean diet representing an important source of proteins, fiber, some minerals and vitamins and bioactive compounds. We evaluated the antioxidant and anti-mutagenic effects of a new fermented powder of a selected lectin-free and phaseolamin-enriched variety of common bean (Phaseolus vulgaris L.), named Lady Joy. Lady Joy lysate (Lys LJ) was studied in human erythrocytes and in Saccharomyces cerevisiae yeast cells. The antioxidant and anti-hemolytic properties of Lys LJ, studied in an ex vivo erythrocytes system using the cellular antioxidant assay (CAA-RBC) and the hemolysis test, evidenced a dose-dependent antioxidant activity as well as a significant hemolysis inhibition. Besides, results evidenced that Lys LJ treatment significantly decreased the intracellular ROS concentration and mutagenesis induced by hydrogen peroxide in S. cerevisiae D7 strain. In conclusion, Lys LJ showed both an antimutagenic effect in yeast and a strong scavenging activity in yeast and human cells. (literal)

Prodotto di

• Institute of agricultural biology and biotechnology (IBBA) (Istituto)

Autore CNR

• VINCENZO LONGO (Unità di personale interno)
• LAURA PUCCI (Unità di personale interno)
• MORENA GABRIELE (Unità di personale esterno)
• STEFANIA FRASSINETTI (Persona)
• LEONARDO CALTAVUTURO (Unità di personale interno)

Incoming links:

Prodotto

• Institute of agricultural biology and biotechnology (IBBA) (Istituto)

Autore CNR di

• STEFANIA FRASSINETTI (Persona)
• VINCENZO LONGO (Unità di personale interno)
• LEONARDO CALTAVUTURO (Unità di personale interno)
• LAURA PUCCI (Unità di personale interno)
• MORENA GABRIELE (Unità di personale esterno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Plant foods for human nutrition (Rivista)