Some preliminary matrix-assisted laser desorption/ionization imaging experiments on maternal and fetal sides of human placenta (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Some preliminary matrix-assisted laser desorption/ionization imaging experiments on maternal and fetal sides of human placenta (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1255/ejms.1274 (literal)

Alternative label

• Roverso M.; Lapolla A.; Cosma C.; Seraglia R.; Galvan E.; Visentin S.; Cosmi E.; Desoye G.; Traldi P. (2014)
  Some preliminary matrix-assisted laser desorption/ionization imaging experiments on maternal and fetal sides of human placenta
  in European journal of mass spectrometry (Online)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Roverso M.; Lapolla A.; Cosma C.; Seraglia R.; Galvan E.; Visentin S.; Cosmi E.; Desoye G.; Traldi P. (literal)

Pagina inizio

• 261 (literal)

Pagina fine

• 269 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.impublications.com/content/abstract?code=E20_0261 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 20 (literal)

Rivista

• European journal of mass spectrometry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Note

• ISI Web of Science (WOS) (literal)
• Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1-3 : Dipartimento di Medicina, Università Degli Studi di Padova, Via Giustiniani 2, I-35100 Padova, Italy / 4,9 : IENI CNR, Corso Stati Uniti 4, I-35100 Padova, Italy / 5-7 : Dipartimento di Salute della Donna e Del Bambino, Università di Padova, Via Giustiniani 2, I-35100 Padova, Italy / 8 : Department of Obstetrics and Gynecology, Medical University of Graz, Austria (literal)

Titolo

• Some preliminary matrix-assisted laser desorption/ionization imaging experiments on maternal and fetal sides of human placenta (literal)

Abstract

• An investigation on placenta proteins has been carried out by matrix-assisted laser desorption/ionization (MALDI) ion imaging (II) experiments. This was performed by laser irradiation of the maternal and fetal sides of placenta tissue. To investigate the possible changes in protein profile due to the development of gestational diabetes mellitus (GDM), five placenta samples from GDM patients and five placentasamples from healthy pregnant women were analyzed. An extensive optimization of the tissue slice treatment and of the matrix deposition method was performed. As already observed in MALDI spectra of placenta homogenates, and also in the MALDI-II condition, the most abundant peaks are due to hemoglobin ? chain, hemoglobin ? chain and hemoglobin ? chain. However, higher molecular weight protein species were detected in the m/z range 20, 000-47, 000. The species at m/z 30335, m/z 31235 and m/z 32000 show some differences in their abundance in the maternal and fetal sides of the tissue in both classes of subjects under investigation. Comparison with the literature data suggest that they can result from the presence of mitochondrial proteins at tissue level. © 2014 IM Publications LLP. (literal)

Prodotto di

• Institute of Condensed Matter Chemistry and Energy Technologies (ICMATE) (Istituto)
• Identificazione biomarcatori proteici per diabete, nefropatie e tumori mediante spettrometria di massa (PM.P06.008.001) (Modulo)

Autore CNR

• ROBERTA SERAGLIA (Persona)

Insieme di parole chiave

• Parole chiave di "Some preliminary matrix-assisted laser desorption/ionization imaging experiments on maternal and fetal sides of human placenta" (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of Condensed Matter Chemistry and Energy Technologies (ICMATE) (Istituto)
• Identificazione biomarcatori proteici per diabete, nefropatie e tumori mediante spettrometria di massa (PM.P06.008.001) (Modulo)

Autore CNR di

• ROBERTA SERAGLIA (Persona)
• http://www.cnr.it/ontology/cnr/individuo/unitaDiPersonaleEsterno/ID25618

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• European journal of mass spectrometry (Rivista)

Insieme di parole chiave di

• Parole chiave di "Some preliminary matrix-assisted laser desorption/ionization imaging experiments on maternal and fetal sides of human placenta" (Insieme di parole chiave)