Water diffusion anisotropy in white and gray matter of the human spinal cord (Articolo in rivista)

Type
Label
  • Water diffusion anisotropy in white and gray matter of the human spinal cord (Articolo in rivista) (literal)
Anno
  • 2008-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1002/jmri.21252 (literal)
Alternative label
  • Rossi, C; Boss, A; Steidle, G; Martirosian, P; Klose, U; Capuani, S; Maraviglia, B; Claussen, CD; Schick, F (2008)
    Water diffusion anisotropy in white and gray matter of the human spinal cord
    in Journal of magnetic resonance imaging (Print)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Rossi, C; Boss, A; Steidle, G; Martirosian, P; Klose, U; Capuani, S; Maraviglia, B; Claussen, CD; Schick, F (literal)
Pagina inizio
  • 476 (literal)
Pagina fine
  • 482 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 27 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 3 (literal)
Note
  • ISI Web of Science (WOS) (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • \"[Rossi, Cristina; Boss, Andreas; Steidle, Guenter; Martirosian, Petros; Claussen, Claus D.; Schick, Fritz] Univ Tubingen, Sect Expt Radiol, Dept Diagnost Radiol, D-72076 Tubingen, Germany; [Rossi, Cristina; Capuani, Silvia] Univ Roma La Sapienza, CNR, INFM, Rome, Italy; [Klose, Uwe] Univ Tubingen, Dept Neuroradiol, Sect Expt MR CNS, D-7400 Tubingen, Germany; [Maraviglia, Bruno] Univ Roma La Sapienza, Dept Phys, I-00185 Rome, Italy; [Maraviglia, Bruno] IRCCS, Santa Lucia Fdn, Rome, Italy (literal)
Titolo
  • Water diffusion anisotropy in white and gray matter of the human spinal cord (literal)
Abstract
  • \"Purpose: To develop a reliable technique for diffusion imaging of the human spinal cord at 1.5 Tesla and to assess potential differences in diffusion anisotropy in cross-sectional images. Materials and Methods: A single-shot echo-planar imaging sequence with double spin-echo diffusion preparation was optimized regarding cerebrospinal fluid artifacts, effective resolution, and contrast-to-noise ratios. Eleven healthy volunteers participated in the study for quantitative characterization of diffusion anisotropy in white matter (WM) and gray matter (GM) by means of two diffusion encoding schemes: octahedral-six-directions for fractional anisotropy (FA) evaluation and orthogonal-three-directions for anisotropy index (AI) calculation. Results: Pulse-trigger gated sequences with optimal matrix size (read X phase = 64 X 32) and b-value (700 s/mm(2)) allowed the acquisition of high-resolved images (voxel Size = 0.9 X 0.9 X 5.0 mm(3)). The GM butterfly shape was recognizable in both AI and FA maps. Both encoding schemes yielded high diffusion anisotropy in dorsal WM (FA = 0.79 +/- 0.07; AI = 0.39 +/- 0.04). Lateral WM showed slightly lower anisotropy (FA 0.69 +/- 0.08; AI = 0.35 +/- 0.03) than dorsal WM. Clearly smaller anisotropy was found in regions containing GM (FA = 0.45 +/- 0.06; AI = 0.21 +/- 0.05). Conclusion: Diffusion anisotropy data of the spinal cord can be obtained in a clinical setting. Its application seems promising for the assessment of neurological disorders.\" (literal)
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