Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: An application of item response theory (Articolo in rivista)

Type
Label
  • Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: An application of item response theory (Articolo in rivista) (literal)
Anno
  • 2014-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1007/s10519-014-9654-x (literal)
Alternative label
  • Van Den Berg S.M.; De Moor M.H.M.; McGue M.; Pettersson E.; Terracciano A.; Verweij K.J.H.; Amin N.; Derringer J.; Esko T.; Van Grootheest G.; Hansell N.K.; Huffman J.; Konte B.; Lahti J.; Luciano M.; Matteson L.K.; Viktorin A.; Wouda J.; Agrawal A.; Allik J.; Bierut L.; Broms U.; Campbell H.; Smith G.D.; Eriksson J.G.; Ferrucci L.; Franke B.; Fox J.-P.; De Geus E.J.C.; Giegling I.; Gow A.J.; Grucza R.; Hartmann A.M.; Heath A.C.; Heikkila K.; Iacono W.G.; Janzing J.; Jokela M.; Kiemeney L.; Lehtimaki T.; Madden P.A.F.; Magnusson P.K.E.; Northstone K.; Nutile T.; Ouwens K.G.; Palotie A.; Pattie A.; Pesonen A.-K.; Polasek O.; Pulkkinen L.; Pulkki-Raback L.; Raitakari O.T.; Realo A.; Rose R.J.; Ruggiero D.; Seppala I.; Slutske W.S.; Smyth D.C.; Sorice R.; Starr J.M.; Sutin A.R.; Tanaka T.; Verhagen J.; Vermeulen S.; Vuoksimaa E.; Widen E.; Willemsen G.; Wright M.J.; Zgaga L.; Rujescu D.; Metspalu A.; Wilson J.F.; Ciullo M.; Hayward C.; Rudan I.; Deary I.J.; Raikkonen K.; Arias Vasquez A.; Costa P.T.; Keltikangas-Jarvinen L.; Van Duijn C.M.; Penninx B.W.J.H.; Krueger R.F.; Evans D.M.; Kaprio J.; Pedersen N.L.; Martin N.G.; Boomsma D.I. (2014)
    Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: An application of item response theory
    in Behavior genetics
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Van Den Berg S.M.; De Moor M.H.M.; McGue M.; Pettersson E.; Terracciano A.; Verweij K.J.H.; Amin N.; Derringer J.; Esko T.; Van Grootheest G.; Hansell N.K.; Huffman J.; Konte B.; Lahti J.; Luciano M.; Matteson L.K.; Viktorin A.; Wouda J.; Agrawal A.; Allik J.; Bierut L.; Broms U.; Campbell H.; Smith G.D.; Eriksson J.G.; Ferrucci L.; Franke B.; Fox J.-P.; De Geus E.J.C.; Giegling I.; Gow A.J.; Grucza R.; Hartmann A.M.; Heath A.C.; Heikkila K.; Iacono W.G.; Janzing J.; Jokela M.; Kiemeney L.; Lehtimaki T.; Madden P.A.F.; Magnusson P.K.E.; Northstone K.; Nutile T.; Ouwens K.G.; Palotie A.; Pattie A.; Pesonen A.-K.; Polasek O.; Pulkkinen L.; Pulkki-Raback L.; Raitakari O.T.; Realo A.; Rose R.J.; Ruggiero D.; Seppala I.; Slutske W.S.; Smyth D.C.; Sorice R.; Starr J.M.; Sutin A.R.; Tanaka T.; Verhagen J.; Vermeulen S.; Vuoksimaa E.; Widen E.; Willemsen G.; Wright M.J.; Zgaga L.; Rujescu D.; Metspalu A.; Wilson J.F.; Ciullo M.; Hayward C.; Rudan I.; Deary I.J.; Raikkonen K.; Arias Vasquez A.; Costa P.T.; Keltikangas-Jarvinen L.; Van Duijn C.M.; Penninx B.W.J.H.; Krueger R.F.; Evans D.M.; Kaprio J.; Pedersen N.L.; Martin N.G.; Boomsma D.I. (literal)
Pagina inizio
  • 295 (literal)
Pagina fine
  • 313 (literal)
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  • http://www.scopus.com/inward/record.url?eid=2-s2.0-84903820211&partnerID=q2rCbXpz (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 44 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 4 (literal)
Note
  • Scopu (literal)
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  • Department of Research Methodology, Measurement and Data-Analysis, University of Twente, Enschede, Netherlands; Department of Biological Psychology, VU University, Amsterdam, Netherlands; Department of Psychology, University of Minnesota, Elliott Hall, Minneapolis, MN, United States; Institute of Public Health, University of Southern Denmark, Odense, Denmark; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; National Institute on Aging, NIH, Baltimore, MD, United States; College of Medicine, Florida State University, Tallahassee, FL, United States; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia; Department of Developmental Psychology, EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Psychology, University of Illinois at Urbana-Champaign, Champaign, IL, United States; Estonian Genome Center, University of Tartu, Tartu, Estonia; Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Center Amsterdam, Amsterdam, Netherlands; MRC Human Genetics, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom; Department of Psychiatry, University of Halle, Halle, Germany; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland; Folkhälsan Research Center, Helsinki, Finland; Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States; Department of Psychology, University of Tartu, Tartu, Estonia; Estonian Academy of Sciences, Tallinn, Estonia; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland; National Institute for Health and Welfare (THL), Helsinki, Finland; Centre for Population Health Sciences, Medical School, University of Edinburgh, Edinburgh, United Kingdom; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland; Vasa Central Hospital, Vaasa, Finland; Donders Institute for Cognitive Neuroscience, Radboud University Nijmegen, Nijmegen, Netherlands; Department of Psychiatry, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; Department of Human Genetics, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; Department of Psychology, School of Life Sciences, Heriot-Watt University, Edinburgh, United Kingdom; Department of Clinical Chemistry, School of Medicine, University of Tampere, Tampere, Finland; Department of Health Evidence, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; Department of Urology, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR, Naples, Italy; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia; Department of Psychology, University of Jyväskylä, Jyväskylä, Finland; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States; Department of Psychological Sciences, Missouri Alcoholism Research Center, University of Missouri, Columbia, MO, United States; Department of Psychological Methods, University of Amsterdam, Amsterdam, Netherlands; Department of Psychiatry, University of California, San Diego, CA, United States; Department of Public Health and Primary Care, Trinity College Dublin, Dublin, Ireland; Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; Behavioral Medicine Research Center, Duke University School of Medicine, Durham, NC, United States; Department of Behavioural Sciences, OMD, University of Twente, PO Box 217, 7500 AE Enschede, Netherlands (literal)
Titolo
  • Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: An application of item response theory (literal)
Abstract
  • Mega- or meta-analytic studies (e.g. genome-wide association studies) are increasingly used in behavior genetics. An issue in such studies is that phenotypes are often measured by different instruments across study cohorts, requiring harmonization of measures so that more powerful fixed effect meta-analyses can be employed. Within the Genetics of Personality Consortium, we demonstrate for two clinically relevant personality traits, Neuroticism and Extraversion, how Item-Response Theory (IRT) can be applied to map item data from different inventories to the same underlying constructs. Personality item data were analyzed in >160,000 individuals from 23 cohorts across Europe, USA and Australia in which Neuroticism and Extraversion were assessed by nine different personality inventories. Results showed that harmonization was very successful for most personality inventories and moderately successful for some. Neuroticism and Extraversion inventories were largely measurement invariant across cohorts, in particular when comparing cohorts from countries where the same language is spoken. The IRT-based scores for Neuroticism and Extraversion were heritable (48 and 49 %, respectively, based on a meta-analysis of six twin cohorts, total N = 29,496 and 29,501 twin pairs, respectively) with a significant part of the heritability due to non-additive genetic factors. For Extraversion, these genetic factors qualitatively differ across sexes. We showed that our IRT method can lead to a large increase in sample size and therefore statistical power. The IRT approach may be applied to any mega- or meta-analytic study in which item-based behavioral measures need to be harmonized. © 2014 The Author(s). (literal)
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