http://www.cnr.it/ontology/cnr/individuo/prodotto/ID294650
Serous cutaneous glands in anurans: Fourier transform analysis of the repeating secretory granule substructure (Articolo in rivista)
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- Serous cutaneous glands in anurans: Fourier transform analysis of the repeating secretory granule substructure (Articolo in rivista) (literal)
- Anno
- 2013-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1007/s00114-013-1013-x (literal)
- Alternative label
Nosi, D.; Delfino, G.; Quercioli, F. (2013)
Serous cutaneous glands in anurans: Fourier transform analysis of the repeating secretory granule substructure
in Naturwissenschaften
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- Nosi, D.; Delfino, G.; Quercioli, F. (literal)
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- Department of Anatomy, Histology, and Forensic Medicine, University of Florence, Viale Morgagni 85, 50134 Florence, Italy; Department of Evolutionary Biology, University of Florence, Via Romana 17, 50125 Florence, Italy; Consiglio Nazionale Delle Ricerche Florence Research Area, National Institute of Optics, Via Nello Carrara 1, 50019 Sesto Fiorentino (Florence), Italy (literal)
- Titolo
- Serous cutaneous glands in anurans: Fourier transform analysis of the repeating secretory granule substructure (literal)
- Abstract
- A combined transmission electron microscopy (TEM) and Fourier transform analysis has been performed on the secretory granules storing active peptides/proteins in serous cutaneous glands of n = 12 anuran species. Previous TEM investigation showed that the granules are provided with remarkable repeating substructures based on discrete subunits, arranged into a consistent framework. Furthermore, TEM findings revealed that this recurrent arrangement is acquired during a prolonged post-Golgian (or maturational) processing that affects the secretory product. Maturation leads to a variety of patterns depending on the degree of subunit clustering. This variety of recurrent patterns has been plotted into a range of frequency spectra. Through this quantitative approach, we found that the varying granule substructure can be reduced to a single mechanism of peptide/protein aggregation. (literal)
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