Regularized ML reconstruction for time/dose reduction in 18F-fluoride PET/CT studies. (Articolo in rivista)

Type
Label
  • Regularized ML reconstruction for time/dose reduction in 18F-fluoride PET/CT studies. (Articolo in rivista) (literal)
Anno
  • 2015-01-01T00:00:00+01:00 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
  • 10.1088/0031-9155/60/1/67 (literal)
Alternative label
  • Elisabetta De Bernardi1,2, Patrizia Magnani2, Luigi Gianolli2, Maria Carla Gilardi1,2,3 and Valentino Bettinardi2 (2015)
    Regularized ML reconstruction for time/dose reduction in 18F-fluoride PET/CT studies.
    in Physics in medicine & biology (Online)
    (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
  • Elisabetta De Bernardi1,2, Patrizia Magnani2, Luigi Gianolli2, Maria Carla Gilardi1,2,3 and Valentino Bettinardi2 (literal)
Pagina inizio
  • 67 (literal)
Pagina fine
  • 80 (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
  • 60 (literal)
Rivista
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo
  • 1 (literal)
Note
  • PubMe (literal)
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
  • 1 Department of Health Sciences--Tecnomed Foundation, University of Milano-Bicocca, 20900 Monza, Italy 2 Department of Nuclear Medicine, IRCCS, San Raffaele Scientific Institute, 20132 Milano, Italy 3 IBFM-CNR, Institute for Molecular Bioimaging and Physiology, 20090 Segrate, Italy (literal)
Titolo
  • Regularized ML reconstruction for time/dose reduction in 18F-fluoride PET/CT studies. (literal)
Abstract
  • We are proposing a regularized reconstruction strategy for the detection of bone lesions in 18F-fluoride whole body PET images obtained with 1 min/bed using the anatomical information provided by co-registered CT images. Bones are recognized on CT images and then transposed into the PET volume framework. During PET reconstruction, two different priors are used for bone and non-bone voxels: the relative difference prior in bone and the P-Gaussian prior in non-bone. After a tuning of the priors' parameters, the reconstruction strategy has been tested on 6 18F-fluoride PET/CT studies, on a total of 67 lesions. Regularized images provided results comparable to the standard 3 min/bed images, in terms image quality, lesion activity, noise level and noise correlation. The proposed strategy therefore appears to be a useful tool to reduce the acquisition time or the injected dose in 18F-fluoride PET studies. (literal)
Prodotto di
Autore CNR
Insieme di parole chiave

Incoming links:


Prodotto
Autore CNR di
Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi
Insieme di parole chiave di
data.CNR.it