Investigation on the stability of DON and DON-3 glucoside during gastro-duodenal in vitro digestion of a naturally contaminated bread model food (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Investigation on the stability of DON and DON-3 glucoside during gastro-duodenal in vitro digestion of a naturally contaminated bread model food (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.foodcont.2014.03.032 (literal)

Alternative label

• De Angelis, Elisabetta; Monaci, Linda; Visconti, Angelo (2014)
  Investigation on the stability of DON and DON-3 glucoside during gastro-duodenal in vitro digestion of a naturally contaminated bread model food
  in Food control
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• De Angelis, Elisabetta; Monaci, Linda; Visconti, Angelo (literal)

Pagina inizio

• 270 (literal)

Pagina fine

• 275 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 43 (literal)

Rivista

• Food control (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 6 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Consiglio Nazionale delle Ricerche (CNR)-ISPA (literal)

Titolo

• Investigation on the stability of DON and DON-3 glucoside during gastro-duodenal in vitro digestion of a naturally contaminated bread model food (literal)

Abstract

• Deoxynivalenol (DON) and its main conjugate derivative, DON-3 glucoside (DON-3G), are Fusarium mycotoxins frequently occurring in cereal and cereal-based products destined to human consumption. In this paper, we investigated the stability of DON and DON-3G along the gastric and duodenal-jejunal tract (GI) by submitting a bread food naturally contaminated with both mycotoxins to in vitro digestion experiments. Gastro-duodenal digestion fluids were collected at different time-points along the whole digestion process (gastric and duodenal phases) and mycotoxin content was determined by LC/High Resolution Mass Spectrometry. Our findings show a rather stable behaviour displayed by DON during gastric digestion, whereas a 43% DON decrease was recorded during the passage from the gastric to the duodenal compartment. Ultimately, the apparent and actual bioaccessibility was calculated for DON with values ranging between 34 and 57%, respectively. Data obtained for DON-3G showed no significant differences between the beginning and the end of the gastric phase, whereas a remarked increase of this conjugated mycotoxin was highlighted during the passage in the duodenal compartment. Our results suggest that a conversion of DON in DON-3G is likely to occur during gastro-duodenal digestion of contaminated bread. (literal)

Prodotto di

• Metodi innovativi per l'analisi e la riduzione di micotossine, funghi tossigeni ed allergeni nei prodotti agroalimentari (AG.P05.008.002) (Modulo)
• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)

Autore CNR

• LINDA MONACI (Unità di personale interno)
• ELISABETTA DE ANGELIS (Persona)
• ANGELO VISCONTI (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Investigation on the stability of DON and DON-3 glucoside during gastro-duodenal in vitro digestion of a naturally contaminated bread model food" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANGELO VISCONTI (Unità di personale interno)
• ELISABETTA DE ANGELIS (Persona)
• LINDA MONACI (Unità di personale interno)

Prodotto

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)
• Metodi innovativi per l'analisi e la riduzione di micotossine, funghi tossigeni ed allergeni nei prodotti agroalimentari (AG.P05.008.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Food control (Rivista)

Insieme di parole chiave di

• Keywords of "Investigation on the stability of DON and DON-3 glucoside during gastro-duodenal in vitro digestion of a naturally contaminated bread model food" (Insieme di parole chiave)