A Quaternary Nitronyl Nitroxide alpha-Amino Acid: Synthesis, Configurational and Conformational Assignments, and Physicochemical Properties (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• A Quaternary Nitronyl Nitroxide alpha-Amino Acid: Synthesis, Configurational and Conformational Assignments, and Physicochemical Properties (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1002/ejoc.201301765 (literal)

Alternative label

• Wright, K.; d'Aboville, E.; Scola, J.; Margola, T.; Toffoletti, A.; De Zotti, M.; Crisma, M.; Formaggio, F.; Toniolo, C. (2014)
  A Quaternary Nitronyl Nitroxide alpha-Amino Acid: Synthesis, Configurational and Conformational Assignments, and Physicochemical Properties
  in European journal of organic chemistry (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Wright, K.; d'Aboville, E.; Scola, J.; Margola, T.; Toffoletti, A.; De Zotti, M.; Crisma, M.; Formaggio, F.; Toniolo, C. (literal)

Pagina inizio

• 1741 (literal)

Pagina fine

• 1752 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 2014 (literal)

Rivista

• European journal of organic chemistry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 12 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 8 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• ILV, UMR 8180, University of Versailles, 78035 Versailles, France; GEMAC, UMR 8635, University of Versailles, 78035 Versailles, France; Department of Chemistry, University of Padova, 35131 Padova, Italy; Institute of Biomolecular Chemistry, Padova Unit, CNR, 35131 Padova, Italy (literal)

Titolo

• A Quaternary Nitronyl Nitroxide alpha-Amino Acid: Synthesis, Configurational and Conformational Assignments, and Physicochemical Properties (literal)

Abstract

• To expand the presently extremely limited repertoire of known nitronyl nitroxide -amino acids, we report here the synthesis of a novel, conformationally constrained, quaternary, chiral residue, Aic(CN), and its subsequent conversion into a blue-colored, imidazolinyl nitronyl nitroxide-bearing -amino acid, Aic(NN). Deprotection and peptide coupling reactions were examined. The configurational assignment of Aic(NN) was achieved by X-ray crystallographic analysis of an appropriate tripeptide. This latter investigation, accompanied by an IR absorption conformational analysis, strongly supports the view that the Aic(NN) residue is an efficient peptide turn former. Numerous spectroscopic and magnetic properties of its derivatives and the tripeptide are also described. Of particular relevance for future applications are its UV/Vis absorption, NMR, and EPR signatures. (literal)

Prodotto di

• Istituto di chimica biomolecolare (ICB) (Istituto)
• Peptidi da amminoacidi non proteici con potenzialità in nanomedicina (PM.P01.021.001) (Modulo)

Autore CNR

• MARCO CRISMA (Unità di personale interno)
• CLAUDIO TONIOLO (Persona)
• FERNANDO FORMAGGIO (Unità di personale esterno)

Insieme di parole chiave

• Keywords of "A Quaternary Nitronyl Nitroxide alpha-Amino Acid: Synthesis, Configurational and Conformational Assignments, and Physicochemical Properties" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• MARCO CRISMA (Unità di personale interno)
• CLAUDIO TONIOLO (Persona)
• FERNANDO FORMAGGIO (Unità di personale esterno)

Prodotto

• Istituto di chimica biomolecolare (ICB) (Istituto)
• Peptidi da amminoacidi non proteici con potenzialità in nanomedicina (PM.P01.021.001) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• European journal of organic chemistry (Rivista)

Insieme di parole chiave di

• Keywords of "A Quaternary Nitronyl Nitroxide alpha-Amino Acid: Synthesis, Configurational and Conformational Assignments, and Physicochemical Properties" (Insieme di parole chiave)