Rh-catalyzed asymmetric hydrogenation using a furanoside monophosphite second-generation ligand library: scope and limitations (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Rh-catalyzed asymmetric hydrogenation using a furanoside monophosphite second-generation ligand library: scope and limitations (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.tetasy.2013.12.010 (literal)

Alternative label

• Alegre, Sabina; Alberico, Elisabetta; Pamies, Oscar; Dieguez, Montserrat (2014)
  Rh-catalyzed asymmetric hydrogenation using a furanoside monophosphite second-generation ligand library: scope and limitations
  in Tetrahedron: asymmetry (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Alegre, Sabina; Alberico, Elisabetta; Pamies, Oscar; Dieguez, Montserrat (literal)

Pagina inizio

• 258 (literal)

Pagina fine

• 262 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 25 (literal)

Rivista

• Tetrahedron: asymmetry (Rivista)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#pagineTotali

• 5 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroFascicolo

• 3 (literal)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• Universitat Rovira i Virgili; Consiglio Nazionale delle Ricerche (CNR) (literal)

Titolo

• Rh-catalyzed asymmetric hydrogenation using a furanoside monophosphite second-generation ligand library: scope and limitations (literal)

Abstract

• The ligand design of one of the most successful monophosphite ligand classes in Rh-catalyzed hydrogenation was expanded upon by introducing several substituents at the C-3 position of the furanoside backbone. A small but structurally important library of monophosphite ligands was developed by changing the substituents at the C-3 position of the furanoside backbone and the substituents/configurations at the biaryl phosphite group. These new furanoside monophosphite ligands were evaluated in the Rh-catalyzed asymmetric hydrogenation of alpha,beta-unsaturated carboxylic acid derivatives and enamides. The results show that the effect of introducing a substituent at the C-3 position of the furanoside backbone on the enantioselectivity depends not only on the configuration at the C-3 position of the furanoside backbone and the binaphthyl group but also on the substrate. Thus, the new ligands afforded high to excellent enantioselectivities in the reduction of carboxylic acid derivatives (ee's up to >99.9%) and moderate ee's (up to 67%) in the hydrogenation of enamides. (C) 2013 Elsevier Ltd. All rights reserved. (literal)

Prodotto di

• Institute of biomolecular chemistry (ICB) (Istituto)
• Catalizzatori ad alta selettività in reazioni di idroformilazione ed idrogenazione (PM.P03.002.005) (Modulo)

Autore CNR

• ELISABETTA ALBERICO (Persona)

Incoming links:

Autore CNR di

• ELISABETTA ALBERICO (Persona)

Prodotto

• Institute of biomolecular chemistry (ICB) (Istituto)
• Catalizzatori ad alta selettività in reazioni di idroformilazione ed idrogenazione (PM.P03.002.005) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Tetrahedron: asymmetry (Rivista)