Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples (Articolo in rivista)

Type

• Articolo in rivista (Classe)
• Prodotto della ricerca (Classe)

Label

• Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples (Articolo in rivista) (literal)

Anno

• 2014-01-01T00:00:00+01:00 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi

• 10.1016/j.fct.2014.01.039 (literal)

Alternative label

• Minervini F.; Debellis L.; Garbetta A.; De Girolamo A.; Schena R.; Portincasa P.; Visconti A. (2014)
  Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples
  in Food and chemical toxicology
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Minervini F.; Debellis L.; Garbetta A.; De Girolamo A.; Schena R.; Portincasa P.; Visconti A. (literal)

Pagina inizio

• 166 (literal)

Pagina fine

• 172 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#url

• http://www.scopus.com/inward/record.url?eid=2-s2.0-84894136470&partnerID=q2rCbXpz (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 66 (literal)

Rivista

• Food and chemical toxicology (Rivista)

Note

• Scopu (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• National Research Council of Italy (CNR), Institute of Sciences of Food Production (ISPA), Via G. Amendola 122/O, 70125 Bari, Italy; Department of Bioscience, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy; Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Piazza G. Cesare, 70100 Bari, Italy (literal)

Titolo

• Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples (literal)

Abstract

• [object Object]The gut is a possible target toward mycotoxin fumonisins (FBs) exposure. The study aims to investigate the effects induced by FBs contaminated-corn chyme samples on functional parameters of human and rat intestine by using Ussing chamber. Fumonisins-contaminated corn and processed corn samples were undergone to in vitro digestion process and then added to luminal side. A reduction (about 90%) of short circuit current (Isc lA/cm2) during exposure of human colon tissues to fumonisins-free corn chyme samples was observed, probably related to increased chyme osmolality. This hyperosmotic stress could drain water towards the luminal compartment, modifying Na+ and Cl? transports. The presence of FBs in corn chyme samples, independently to their concentration, did not affect significantly the Isc, probably related to their interference towards epithelial Na+ transport, as assessed by using a specific inhibitor (Amiloride). The rat colon tract represents a more accessible model to study FBs toxicity showing a similar functional response to human. In the rat small intestine a significant reduction (about 15%) of Isc parameter during exposure to uncontaminated or FBs contaminated corn chyme samples was observed; therefore such model was not suitable to assess the FBs toxicity, probably because the prevalent glucose and amino acids electrogenic absorption overwhelmed the FBs influence on ionic transport. (literal)

Prodotto di

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)
• Metodi innovativi per l'analisi e la riduzione di micotossine, funghi tossigeni ed allergeni nei prodotti agroalimentari (AG.P05.008.002) (Modulo)

Autore CNR

• Antonella Garbetta (Persona)
• ANNALISA DE GIROLAMO (Unità di personale interno)
• ANGELO VISCONTI (Unità di personale interno)
• ROBERTO SCHENA (Unità di personale esterno)
• FIORENZA MINERVINI (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples" (Insieme di parole chiave)

Incoming links:

Autore CNR di

• ANGELO VISCONTI (Unità di personale interno)
• ANNALISA DE GIROLAMO (Unità di personale interno)
• FIORENZA MINERVINI (Unità di personale interno)
• Antonella Garbetta (Persona)
• ROBERTO SCHENA (Unità di personale esterno)

Prodotto

• Istituto di scienze delle produzioni alimentari (ISPA) (Istituto)
• Metodi innovativi per l'analisi e la riduzione di micotossine, funghi tossigeni ed allergeni nei prodotti agroalimentari (AG.P05.008.002) (Modulo)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Food and chemical toxicology (Rivista)

Insieme di parole chiave di

• Keywords of "Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples" (Insieme di parole chiave)